research cblee members publications photos links
  • "Ruthenium-Catalyzed Carboxylative Cyclization of 1,6-Diynes," H. Kim, S. D. Goble, and C. Lee, J. Am. Chem. Soc., 129, 1030-1031 (2007).

  • "Rhodium-Catalyzed Arylative and Alkenylative Cyclization of 1,5-Enynes Induced by Geminal Carbometalation of Alkynes," Y. Chen and C. Lee, J. Am. Chem. Soc., 128, 15598-15599 (2006).

  • "Tandem Cyclization of Alkynes via Rhodium Alkynyl and Alkenylidene Catalysis," J. M. Joo, Y. Yuan, and C. Lee, J. Am. Chem. Soc., 128, 14818-14819 (2006).

  • "A Highly Enantio- and Diastereoselective 1,3-Dimethylallylation of Aldehydes," Y. Yuan, A. J. Lai, C. M. Kraml, and C. Lee, Tetrahedron, 62, 11391-11396 (2006).

  • "Rhodium-Catalyzed Cycloisomerization of N-Propargyl Enamine Derivatives," H. Kim and C. Lee, J. Am. Chem. Soc., 128, 6336-6337 (2006).

  • "Ruthenium-Catalyzed Hydrative Cyclization of 1,5-Enynes," Y. Chen, D. M. Ho and C. Lee, J. Am. Chem. Soc., 127, 12184-12185 (2005).

  • "Cycloisomerization of Enynes via Rhodium Vinylidene-Mediated Catalysis," H. Kim and C. Lee, J. Am. Chem. Soc., 127, 10180-10181 (2005).

  • "Allylic Etherification via Ir(I)/Zn(II) Bimetallic Catalysis," J. P. Roberts and C. Lee, Org. Lett., 7, 2679-2682 (2005).

  • "Iridium-catalyzed selective N-allylation of hydrazines," R. Matunas, A. J. Lai and C. Lee, Tetrahedron, 61, 6298-6308 (2005).

  • "Palladium-Catalyzed Ring-Forming Aminoacetoxylation of Alkenes," E. J. Alexanian, C. Lee, and E. J. Sorensen, J. Am. Chem. Soc., 127, 7690 -7691 (2005).

  • "Total Synthesis of Kendomycin: A Macro-C-Glycosidation Approach," Y. Yuan, H. Men and C. Lee, J. Am. Chem. Soc., 126, 14720-14721 (2004).

  • "Stereoselective Palladium-Catalyzed O-Glycosylation Using Glycals," H. Kim, H. Men and C. Lee, J. Am. Chem. Soc., 126, 1336-1337 (2004).

  • "A Mild and Efficient Method for the Stereoselective Formation of C-O Bonds: Palladium-Catalyzed Allylic Etherification Using Zinc(II) Alkoxides," H. Kim and C. Lee, Org. Lett., 4, 4369-4371 (2002).

    Chulbom Postdoctoral Publications
  • "Probing the SAR of dEpoB via Chemical Synthesis: A Total Synthesis Evaluation of C26-(1,3-dioxolanyl)-12,13-desoxyepothilone B," M. D. Chappell, C. R. Harris, S. D. Kudak, A. Balog, Z. Wu, F. Zhang, C. B. Lee, S. J. Stachel, S. J. Danishefsky, T.-C. Chou, Y. Guan, J. Org. Chem., 67, 7730-7736 (2002).

  • "The Synthesis, Discovery, and Development of a Highly Promising Class of Microtubule Stabilization Agents: Curative Effect of Desoxyepothilone B and F against Human Tumor Xenografts in Nude Mice," T.-C. Chou, O. A. O¡¯Connor, W. P. Tong, Y. Guan, X.-G. Zhang, S. J. Stachel, C. Lee, and S. J. Danishefsky, Proc. Natl. Acad. Sci. U.S.A., 98, 8113-8118 (2001).

  • "A New Class of Microtubule Stabilization Agents: Curative Effect of Desoxyepothilone B and F against Human Tumor Xenografts in Nude Mice," T.-C. Chou, Y. Guan, X.-G. Zhang, C. Lee, S. J. Stachel, J. R. Bertino, and S. J. Danishefsky, Proc. Am. Assoc. Cancer Res., 42, 371 (2001).

  • "On the Interactivity of Complex Synthesis and Tumor Pharmacology in the Drug Discovery Process: The Total Synthesis and Comparative in vivo Evaluations of the 15-Aza Epothilones," S. J. Stachel, C. B. Lee, M. Spassova, M. D. Chappell, S. J. Danishefsky, T.-C. Chou, and Y. Guan, J. Org. Chem., 66, 4369-4378 (2001).

  • "Insights into Long Range Structural Effects on the Stereochemistry of Aldol Condensations: A Practical Total Synthesis of Desoxyepothilone F," C. B. Lee, Z. Wu, F. Zhang, M. D. Chappell, S. J. Stachel, T.-C. Chou, Y. Guan, and S. J. Danishefsky, J. Am. Chem. Soc., 123, 5249-5259 (2001).

  • "The Total Synthesis and Antitumor Activity of 12,13-Desoxyepothilone F: An Unexpected Solvolysis Problem at C15, Mediated by Remote Substitution at C21," C. B. Lee, T.-C. Chou, X.-G. Zhang, Z.-G. Wang, S. D. Kuduk, M. D. Chappell, S. J. Stachel and S. J. Danishefsky J. Org. Chem., 65 , 6525-6533 (2000).

  • "On the Total Synthesis and Preliminary Biological Evaluation of 15(R) and 15(S) Aza-dEpoB: A Mitsunobu Inversion at C15 in Pre-Epothilone Fragments," S. J. Stachel, M. D. Chappell, C. B. Lee, S. J. Danishefsky, T.-C. Chou, L. He, and S. B. Horwitz, Org. Lett., 2, 1637-1639 (2000).

  • "En Route to a Plant Scale Synthesis of the Promising Antitumor Agent 12,13-Desoxyepothilone B," M. D. Chappell, S. J. Stachel, C. B. Lee, and S. J. Danishefsky, Org. Lett., 2, 1633-1636 (2000).

    Chulbom Doctoral Publications
  • "gem-Diacetates as Carbonyl Surrogates for Asymmetric Synthesis. Total Syntheses of Sphingofungins E and F," B. M. Trost and C. Lee, J. Am. Chem. Soc., 123 12191-12201 (2001).

  • "Geminal-Dicarboxylates as Carbonyl Surrogates for Asymmetric Synthesis. Part I. Asymmetric Addition of Malonate Nucleophiles," B. M. Trost and C. B. Lee, J. Am. Chem. Soc., 123, 3671-3686 (2001).

  • "Geminal-Dicarboxylates as Carbonyl Surrogates for Asymmetric Synthesis. Part II. Scope and Applications," B. M. Trost and C. B. Lee, J. Am. Chem. Soc., 123, 3687-3696 (2001).

  • "Transition Metal-Catalyzed Asymmetric Allylic Alkylation (AAA) Reactions" B. M. Trost and C. B. Lee In "Catalytic Asymmetric Synthesis (2nd Ed.)," I. Ojima Ed.; Wiley-VCH, New York, NY, 2000, Chapter 8E, pp 593-649.

  • "¥á-Acetoxysulfones as "Chiral Aldehyde" Equivalents," B. M. Trost, M. L. Crawly, and C. B. Lee, J. Am. Chem. Soc., 122, 6120-6121 (2000).

  • "A New Strategy for Synthesis of Sphingosine Analogues. Sphingofungin F," B. M. Trost and C. B. Lee, J. Am. Chem. Soc., 120, 6818-6819 (1998).

  • "Asymmetric Alkylation of Allylic gem-Dicarboxylates," B. M. Trost, C. B. Lee, and J. M. Weiss, J. Am. Chem. Soc., 117 , 7247-7248 (1995).

    Chulbom Undergraduate / Master Publications
  • "¥â-Alkoxyacrylates in Radical Cyclizations: Remarkably Efficient Oxacycle Synthesis," E. Lee, J. S. Tae, C. B. Lee, and C. M. Park, Tetrahedron Lett., 34, 4831-4834 (1993).

  • "Radical Isomerization via Intramolecular ipso Substitution of Aryl Ethers: Aryl Translocation from Oxygen to Carbon," E. Lee, C. B. Lee, J. S. Tae, H. S. Whang, and K. S. Lee, Tetrahedron Lett., 34, 2343-2346. (1993)