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Research Projects
New Devices For Microchip Based Biological Analysis
David Inglis works with Professors James Sturm and Robert
Austin (of the Physics Department) to develop new devices for microchip
based biological analysis. In the current project, ultra rare mutant
cells are identified and separated from the wild type cells for immediate
genetic analysis. This would comprise the front end of an on chip
total genetic analysis system. Cells expressing mutations in antigens
are bound to magnetic nano-particles through antigen antibody binding.
Embedded permanent micro-magnets then force tagged cells to follow
a different path over the chip. |
Micro-Fluidics:
Normal blood being injected into the device |
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Packing:
Cells are injected into the wafer side of a Silicone-Silicon Wafer
sandwich, between which lie the micro-fluidic channels. |
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