Corrosion & Environmental Degradation
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· An artificial knee joint is a more challenging problem. The components move with respect to each other and the implant life should be as long as possible. 
· Corrosion of the metal structural components and fatigue in a corrosive ambient, wear of the polymeric material and fretting with the release of small particles, and the bioactivity of these components must all be considered.
· Fixing the implant to the bones involves a stem that is placed in a hollowed out region of the bone. Bone cement is used to make a mechanical bond with the bone. In more modern devices, the surface of the stem may be porous and coated with hydroxyapatite (the mineral component of bone) to encourage bone growth into the implant for better bonding.
· The wear of the ultrahigh molecular weight polyethylene used for the surface of the components can produce sub-micron debris that is shed into the surrounding tissue. The immune system attempts to remove these particles, but the enzymes released attack the bone and can destroy the prosthetic junction.
From: C. R. Blanchard, 
"Biomaterials: Body Parts of the Future," SwRI Technology Today