Research

research

Molecular Basis of TGF-beta Gene Responses in Human Breast Cancer

(My postdoctoral research at the Memorial Sloan-Kettering Cancer Center)

Papers and manuscripts.

Defective repression of c-myc in breast cancer cells: A loss at the core of the TGF-b growth arrest program.

       Chang-rung Chen*, Yibin Kang* and Joan Massague (2001) Proc. Natl. Acad. Sci.  98: 992-999.PDF version

                   *These authors contributed equally to this work

Meeting presentations and abstracts

Keystone Symposium: Molecular Basis of Cancer: Signal in Cell Growth and Death

Regulation of Eukaryotic Gene Expression
Using Retroviruses as a Model System

(My graduate research at Duke)

Science Link
Virtual Biology--Nuclear-Cytoplasmic Transport
Research proposal for GEN222 (Genetic Analysis of Cellular Functions) (4/97)
Genetics Department Qualification Exam Proposal (1/98)
First thesis committee meeting report (9/98)
Second thesis committee meeting report (4/99)
Thesis defense (4/00)
Papers and manuscripts (supported by the Howard Hughes Medical Institute).

Identification and Functional Characterization of a High Affinity Bel-1 DNA Binding Site Located in the Human Foamy Virus Internal Promoter.

       Yibin Kang, Wade Blair and Bryan R. Cullen (1998) Journal of Virology 72(1):504-511. PDF version

Derivation and Functional Characterization of the Consensus DNA Binding sequence for the Tas Transcriptional Activator of Simian Foamy Virus Type 1.

       Yibin Kang and Bryan R. Cullen (1998) Journal of Virology 72(7):5502-5509. PDF version

The Human Tap Protein is a Nuclear mRNA Export Factor that Contains Novel RNA Binding and Nucleocytoplasmic Transport Sequences.

       Yibin Kang and Bryan R. Cullen (1999) Genes and Development  13(9):1126-1139.PDF version

       Caterina Strambio de Castillia and Michael P. Rout (1999)  Nature Cell Biology 1(2):E31 - E33

       (The review on the G&D paper)   PDF version

Analysis of the RNA Binding Specificity of the Human Tap Nuclear RNA Export Factor.

       Yibin Kang, Hal Bogerd, Jin Yang and Bryan R. Cullen (1999)  Virology 262(1):200-209.

The Human Tap Nuclear RNA Export Factor Contains a Novel Transportin Dependent NLS that Lacks NES Function.

      Ray Truant*,  Yibin Kang*, and Bryan R. Cullen (1999)  Journal of Biological Chemistry   274(45):32167-32171.PDF version 
      *These authors contributed equally to this work

Analysis of Cellular Factors that Mediate Nuclear Export of RNAs Bearing the Mason-pfizer Monkey Virus Constitutive Transport Element.

     Yibin Kang, Hal Bogerd and Bryan R. Cullen (2000) Journal of Virology 74(13):5863-71. PDF version

Nuclear Export of Adenmatous Polyposis Coli Protein Regulates b-Catenin Levels in the Nucleus.

      Kristi L. Neufeld, Dave A. Nix, Hal Bogerd,  Yibin Kang, Mary C. Beckerle, Bryan R. Cullen, and Raymond L. White (2000)      Proc. Natl. Acad. Sci.  97:12085-12090.PDF version

      Glen A. Coburn, Heather L. Wiegand,  Yibin Kang, Dona N. Ho, Mille M. Georgiadis and Bryan R. Cullen (2001)      Genes and Development  in press.PDF version