A.1 Major suppliers of common inbred and outbred strainsa

A.2 Other commercial sources of micea

A.2 Other commercial sources of micea

B.1 On-line electronic databases

B.1 On-line electronic databases

B.2 Mouse Genetics Community Bulletin Board

B.3 Computer Programs

C.1 Selected monographs and books

C.1 Selected monographs and books

C.2 Selected Journals and Serials of Particular Interest

D.1 Confidence limits and median estimates of linkage distance

D.1 Confidence Limits and Median Estimates of Linkage Distance

D.2 Quantitative differences in expression between two strains

Abbott, C. (1992). Characterization of mouse-hamster somatic cell hybrids by PCR: A panel of mouse-specific primers for each chromosome. Mammalian Genome 2: 106-109.

Adolph, S., and Klein, J. (1981). Robertsonian variation in Mus musculus from Central Europe, Spain, and Scotland. J. Hered. 72: 139-142.

Agulnik, A. I., Agulnik, S. I., and Ruvinsky, A. O. (1991). Two doses of the paternal Tme gene do not compensate the lethality of the Thp deletion. J. Hered. 82: 351-353.

Aitman, T. J., Hearne, C. M., McAleer, M. A., and Todd, J. A. (1991). Mononucleotide repeats are an abundant source of length variants in mouse genomic DNA. Mammal. Genome 1: 206-210.

Altman, P. L., and Katz, D., eds. (1979). Inbred and Genetically Defined Strains of Laboratory Animals: Part I, Mouse and Rat. (Fed. Amer. Soc. Exp. Biol., Bethesda).

Alvarez, W., and Asaro, F. (1990, October, 1990). An extraterrestrial impact. Scientific American, p. 78-84.

Ammerman, A. J., and Cavalli-Sforza, L. L. (1984). The Neolithic Transition and the Genetics of Populations in Europe. (Princeton University Press, Princeton, NJ USA).

Armour, J. A. L., and Jeffreys, A. J. (1992). Biology and application of human minisatellite loci. Curr. Opin. Genet. Devel. 2: 850-856.

Arnheim, N. (1983). Concerted evolution of multigene families. In Evolution of Genes and Proteins, Nei, M. and Koehn, R. K., eds. (Sinauer, pp. 38-61.

Arnheim, N., Li, H., and Cui, X. (1991). Review: PCR analysis of DNA sequences in single cells: Single sperm gene mapping and genetic disease diagnosis. Genomics 8: 415-419.

Artzt, K., Calo, C., Pinheiro, E. N., DiMeo, T. A., and Tyson, F. L. (1987). Ovarian teratocarcinomas in LT/Sv mice carrying t-mutations. Dev Genet 8: 1-9.

Asada, Y., Varnum, D. S., Frankel, W. N., and Nadeau, J. H. (1994). A mutation in the Ter gene causing increased susceptibility to testicular teratomas maps to mouse chromosome 18. Nature Genetics 6: 363-368.

Atchley, W. R., and Fitch, W. M. (1991). Gene trees and the origins of inbred strains of mice. Science 254: 554-558.

Auffray, J.-C., Marshall, J. T., Thaler, L., and Bonhomme, F. (1991). Focus on the nomenclature of european species of mus. Mouse Genome 88: 7-8.

Auffray, J.-C., Vanlerberghe, F., and Britton-Davidian, J. (1990). The house mouse progression in Eurasia: a palaeontological and archaeozoological approach. Biol. J. Linnean Soc. 41: 13-25.

Avner, P. (1991). Genetics: Sweet mice, sugar daddies. Nature 351: 519-520.

Avner, P., Amar, L., Dandolo, L., and Guénet, J. L. (1988). Genetic analysis of the mouse using interspecific crosses. Trends Genet. 4: 18-23.

Bahary, N., Pachter, J. E., Felman, R., Leibel, R. L., Albright, K., Cram, S., and Friedman, J. M. (1992). Molecular mapping of mouse chromosomes 4 and 6: use of a flow-sorted Robertsonian chromosome. Genomics 13: 761-769.

Bailey, D. W. (1971). Recombinant-inbred strains. An aid to finding identity, linkage and funcion of histocompatibility and other genes. Transplantation 11: 325-327.

Bailey, D. W. (1978). Sources of subline divergence and their relative importance for sublines of six major inbred strains of mice. In Origins of Inbred Mice, Morse, H. C., eds. (Academic Press, New York), pp. 423-438.

Bailey, D. W. (1981). Recombinant inbred strains and bilineal congenic strains. In The Mouse in Biomedical Research, Vol. 1, Foster, H. L., Small, J. D., and Fox, J. G., eds. (Academic Press, New York), pp. 223-239.

Barany, F. (1991). Genetic disease detection and DNA amplification using cloned thermostable ligase. Proc. Nat. Acad. Sci. USA 88: 189-193.

Barker, D., Schafer, M., and White, R. (1984). Restriction sites containing CpG show a higher frequency of polymorphism in human DNA. Cell 36: 131-138.

Barlow, D., and Lehrach, H. (1990). Partial Not I digests generated by low enzyme concentration or by the presence of ethidium bromide can be used to extend the range of physical mapping. Technique 2: 79-87.

Barlow, D. P., and Leharch, H. (1987). Genetics by gel electrophoresis: the impact of pulsed field gel electrophoresis on mammalian genetics. Trend. Genet. 3: 167-171.

Barlow, D. P., Stoger, R., Herrmann, B. G., Saito, K., and Schweifer, N. (1991). The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus. Nature 349: 84-87.

Bartolomei, M. S., Zemel, S., and Tilghman, S. (1991). Parental imprinting of the mouse H19 gene. Nature 351: 153-155.

Barton, N. H., and Hewitt, G. M. (1989). Adaptation, speciation and hybrid zones. Nature 341: 497-502.

Bateson, W., Saunders, E. R., and Punnett, R. C. (1905). Experimental studies in the physiology of heredity. Reports to the Evolution Committee of the Royal Society 2: 1-55 and 80-99.

Beier, D. R. (1993). Single-strand conformation polymorphism (SSCP) analysis as a tool for genetic mapping. Mammal. Genome 4: 627-631.

Beier, D. R., Dushkin, H., and Sussman, D. J. (1992). Mapping genes in the mouse using single-strand conformation polymorphism analysis of recombinant inbred strains and interspecific crosses. Proc. Nat. Acad. Sci. USA 89: 9102-9106.

Bellvé, A. R., Cavicchia, J. C., Millette, C. F., O’Brien, D. A., Bhatnagar, Y. M., and Dym, M. (1977). Spermatogenic cells of the prepuberal mouse. Isolation and morphological characterization. J. Cell Biol. 74: 68-85.

Berry, R. J. (1981). Population dynamics of the house mouse. Symp. zool. Soc. London 47: 395-425.

Berry, R. J., and Corti, M., eds. (1990). Biological Journal of the Linnean Society (Academic Press, London).

Berry, R. J., and Jakobson, M. E. (1974). Vagility and death in an island population of the house mouse. J. Zool. 173: 341-354.

Berry, R. J., Jakobson, M. E., and Peters, J. (1987). Inherited differences within an island population of the House mouse (Mus domesticus). J. Zool. London 211: 605-618.

Berry, R. J., and Peters, J. (1975). Macquarie Island house mice: a genetical isolate on a sub-Antarctic island. J. Zool. 176: 375-389.

Bickmore, W. A., and Sumner, A. T. (1989). Mammalian chromosome banding - an expression of genome organization. Trend Genet. 5: 144-148.

Bird, A., Lavia, P., MacLeod, D., Lindsay, S., Taggart, M., and Brown, W. (1987). Mammalian genes and islands of non-methylated CpG-rich DNA. In Human Genetics, Vogel, F. and Sperling, K., eds. (Springer-Verlag, Berlin), pp. 182-186.

Bird, A. P. (1986). CpG-rich islands and the function of DNA methylation. Nature 321: 209-213.

Bird, A. P. (1987). CpG islands as gene markers in the vertebrate nucleus. Trend. Genet. 3: 342-347.

Birkenmeier, E., Rowe, L., and Nadeau, J. (1994). The Jackson Laboratory backcross. Mammal. Genome 5: in press.

Bishop, C. E. (1992). Mouse Y chromosome. Mammal. Genome 3: S289-S293.

Bishop, C. E., Boursot, P., Baron, B., Bonhomme, F., and Hatat, D. (1985). Most classical Mus musculus domesticus laboratory mouse strains carry a Mus musculus musculus Y chromosome. Nature 325: 70-72.

Blanchetot, A., Price, M., and Jeffreys, A. J. (1986). The mouse myoglobin gene. Eur. J. Biochem. 159: 469-474.

Bode, V. C. (1984). Ethylnitrosourea mutagenesis and the isolation of mutant alleles for specific genes located in the t-region of mouse chromosome 17. Genetics 108: 457-470.

Boer, P. H., Adra, C. N., Lau, Y.-F., and McBurney, M. W. (1987). The testis-specific phosphoglycerate kinase gene pgk-2 is a recruited retroposon. Mol. Cell. Biol. 7: 3107-3112.

Bohlander, S. K., Espinosa, R., LeBeau, M. M., Rowley, J. D., and Diaz, M. O. (1992). A method for the rapid sequence-independent amplification of microdissected chromosomal material. Genomics 13: 1322-1324.

Bonhomme, F., Benmehdi, F., Britton-Davidian, J., and Martin, S. (1979). Analyse génétique de croisements interspécifiques Mus musculus L. X Mus spretus Lataste: liaison de Adh-1 avec Amy-1 sur le chromosome 3 et de Es-14 avec Mod-1 sur le chromosome 9. C. R. Acad. Sci. Paris 289: 545-548.

Bonhomme, F., Britton-Davidian, J., Thaler, L., and Triantaphyllidis, C. (1978). Sur l’existence en Europe de quatre groupes de souris (genre Mus L.) du rang espèce et semi-espèce, démontrée par la génétique biochimique. C.R. Acad. Sci. Paris 287: 631-633.

Bonhomme, F., Catalan, J., Britton-Davidian, J., V.M., C., Moriwaki, K., Nevo, E., and Thaler, L. (1984). Biochemical diversity and evolution in the genus Mus. Biochem. Genet. 22: 275-303.

Bonhomme, F., Catalan, J., Gerasimov, S., Orsini, P., and Thaler, L. (1983). Le complexe d’espèces du genre Mus en Europe centrale et orientale. I. Génétique. Z. Säugetierkunde 48: 78-85.

Bonhomme, F., and Guénet, J.-L. (1989). The wild house mouse and its relatives. In Genetic Variants and Strains of the Laboratory Mouse., Lyon, M. F. and Searle, A. G., eds. (Oxford University Press, Oxford), pp. 649-662.

Bonhomme, F., Guénet, J.-L., and Catalan, J. (1982). Présence d’un facteur de stérilité mâle, Hst-2, segrégant dans les croisements interspécifiques M. musculus L. x M. Spretus Lastaste et lié à Mod-1 et Mpi-1 sur le chromosome 9. C.R. Acad. Sc. Paris 294 Ser. III: 691-693.

Bonhomme, F., Guénet, J.-L., Dod, B., Moriwaki, K., and Bulfield, G. (1987). The polyphyletic origin of laboratory inbred mice and their rate of evolution. J. Linnean Soc. 30: 51-58.

Bonhomme, F., Martin, S., and Thaler, L. (1978). Hybridation en laboratoire de Mus musculus L. et Mus spretus Lataste. Experientia 34: 1140-1141.

Botstein, D., White, R. L., Skolnick, M., and Davis, R. W. (1980). Construction of a genetic linkage map in man using restriction fragment length polymorphisms. Am. J. Hum. Genet. 32: 314-331.

Boursot, P., Auffray, J.-C., Britton-Davidian, J., and Bonhomme, F. (1993). The evolution of house mice. Ann. Rev. Ecol. System.: in press.

Boursot, P., Bonhomme, F., Britton-Davidian, J., Catalan, J., Yonekawa, H., Orsini, P., Guerasimov, S., and Thaler, L. (1984). Introgression différentielle des génomes nucléaires et mitochondriaux chez deux semi-espèces européennes de Souris. C.R. Acad. Sci. Paris, Série III 299: 365-370.

Boyle, A. L., Ballard, S. G., and Ward, D. C. (1990). Differential distribution of long and short interspersed element sequences in the mouse genome: Chromosome karyotyping by fluorescence in situ hybridization. Proc. Nat. Acad. Sci. 87: 7757-7761.

Boyse, E. A., Miyazawa, M., Aoki, T., and Old, L. J. (1968). Two systems of lymphocyte isoantigens in the mouse. Proc. Royal Soc. (London) B 170: 175-193.

Britton, J., and Thaler, L. (1978). Evidence for the presence of two sympatric species of mice (genus Mus) in southern France based on biochemical genetics. Biochem. Genet. 16: 213-225.

Broccoli, D., Miller, O. J., and Miller, D. A. (1992). Isolation and characterization of a mouse subtelomeric-sequence. Chromosoma 101: 442-447.

Bronson, F. (1984). The adaptability of the house mouse. Sci. Amer. 250: (3) 90-97.

Bronson, F. H., Dagg, C. P., and Snell, G. D. (1966). Reproduction. In Biology of the Laboratory Mouse, Green, E. L., eds. (McGraw-Hill, New York), pp. 187-204.

Brown, S. (1993). The European Collaborative Interspecific Backcross (EUCIB). Mouse Genome 91: v-xii.

Brown, S. D. M., Avner, P., and Herman, G. (1992). Mouse X chromosome. Mammal. Genome 3: S274-S288.

Bruce, H. M. (1959). An exteroreceptive block to pregnancy in the mouse. Nature 184: 105.

Bruce, H. M. (1968). Absence of pregnancy block in mice when stud and test males belong to an inbred strain. J. Reprod. Fert. 17: 407-408.

Bryant, S. P. (1991). Software for genetic linkage analysis. In Protocols in Human Molecular Genetics, Mathew, C. G., eds. (Humana Press, Clifton, NJ),

Bryda, E. C., DePari, J. A., SantAngelo, D. B., Murphy, D. B., and Passmore, H. C. (1992). Multiple sites of crossing over within the Eb recombinational hotspot in the mouse. Mamm Genome 2: 123-9.

Buckler, A. J., Chang, D. D., Graw, S. L., Brook, J. D., Haber, D. A., Sharp, P. A., and Housman, D. E. (1991). Exon amplification: A strategy to isolate mammalian genes based on RNA splicing. Proc Natl Acad Sci USA 88: 4005-4009.

Burke, D. T., Carle, G. F., and Olson, M. V. (1987). Cloning of large segments of exogenous DNA into yeast by means of artificial chromosome vectors. Science 236: 806-812.

Burke, D. T., Rossi, J. M., Koos, D. S., and Tilghman, S. M. (1991). A mouse genomic library of yeast artificial chromosome clones. Mammal. Genome 1: 65.

Cannizzarro, L. A., and Emanuel, B. E. (1984). An improved method for G-banding chromosomes after in situ hybridization. Cytogenet Cell Genet 38: 308-309.

Capecchi, M. (1989). The new mouse genetics: Altering the genome by gene targeting. Trends Genet. 5: 70-76.

Carter, A. T., Norton, J. D., Gibson, Y., and Avery, R. J. (1986). Expression and transmission of a rodent retrovirus-like VL30 gene family. J. Mol. Biol. 188: 105-108.

Carter, T. C. (1954). The estimation of total genetical map lengths from linkage test data. J. Genet. 53: 21-28.

Carter, T. C., and Falconer, D. S. (1951). Stocks for detecting linkage in the mouse and the theory of their design. J. Genet. 50: 307-323.

Castle, W. E. (1903). The laws of Galton and Mendel and some laws governing race improvement by selection. Proc. Amer. Acad. Arts Sci. 35: 233-242.

Cattanach, B. M., and Kirk, M. (1985). Differential activity of maternally and paternally derived chromosome regions in mice. Nature 315: 469-498.

Ceci, J. D., Matsuda, Y., Grubber, J. M., Jenkins, N. A., Copeland, N. G., and Chapman, V. M. (1994). Interspecific backcrosses provide an important tool for centromere mapping of mouse chromosomes. Genomics 19: 515-524.

Chartier, F. L., Keer, J. T., Sutcliffe, M. J., Henriques, D. A., Mileham, P., and Brown, S. D. M. (1992). Construction of a mouse yeast artificial chromosome library in a recombination-deficient strain of yeast. Nature Genetics 1: 132-136.

Chevret, P., Denys, C., Jaeger, J.-J., Michaux, J., and Catzeflis, F. M. (1993). Molecular evidence that the spiny mouse (Acomys) is more closely related to gerbils (Gerbillinae) than to true mice (Murinae). Proc Natl Acad Sci USA 90: 3433-3436.

Chisaka, O., and Capecchi, M. R. (1991). Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5. Nature 350: 473-479.

Chromosome committee chairs (1993). Encyclopedia of the Mouse Genome III. Mammal. Genome 4: special issue: S1-S284.

Chumakov, I., Rigault, P., Guillou, S., Ougen, P., Billaut, A., Guasconi, G., Gervy, P., LeGall, I., Soularue, P., Grinas, L., Bougueleret, L., Bellanne-Chantelot, C., Lacroix, B., Barillot, E., Gesnouin, P., Pook, S., Vaysseix, G., Frelat, G., Schmitz, A., Sambucy, J.-L., Bosch, A., Estivill, X., Weissenbach, J., Vignal, A., Riethman, H., Cox, D., Patterson, D., Gardiner, K., Hattori, M., Sakaki, Y., Ichikawa, H., Ohki, M., Le Paslier, D., Heilig, R., Antonarakis, S., and Cohen, D. (1992). Continuum of overlapping clones spanning the entire human chromosome 21q. Nature 359: 380-387.

Cochran, W. G. (1954). Some methods for strenghening the common c2 tests. Biometrics 10: 417-451.

Collins, F., and Galas, D. (1993). A new five-year plan for the U.S. human genome project. Science 262: 43-46.

Committee on standardized genetic nomenclature for mice (1989). Rules and guidelines for gene nomenclature. In Genetic Variants and Strains of the Laboratory Mouse., Lyon, M. F. and Searle, A. G., eds. (Oxford University Press, Oxford), pp. 1-12.

Cook, M. J. (1983). Anatomy. In The Mouse in Biomedical Research, Vol. 3, Foster, H. L., Small, J. D., and Fox, J. G., eds. (Academic Press, NY), pp. 101-120.

Copeland, N. G., and Jenkins, N. A. (1991). Development and applications of a molecular genetic linkage map of the mouse genome. Trends Genet 7: 113-8.

Copeland, N. G., Jenkins, N. A., Gilbert, D. J., Eppig, J. T., Maltais, L. J., Miller, J. C., Dietrich, W. F., Weaver, A., Lincoln, S. E., Steen, R. G., Stein, L. D., Nadeau, J. H., and Lander, E. S. (1993). A genetic linkage map of the mouse: current applications and future prospects. Science 262: 57-66.

Corbet, G. B., and Hill, J. E. (1991). A World List of Mammalian Species. 3rd edition (Oxford University Press, New York).

Cornall, R. J., Aitman, T. J., Hearne, C. M., and Todd, J. A. (1991). The generation of a library of PCR-analyzed microsatellite variants for genetic mapping of the mouse genome. Genomics 10: 874-881.

Costantini, F., and Lacy, E. (1981). Introduction of a rabbit beta-globin gene into the mouse germ line. Nature 294: 92-94.

Courtney, M. G., Elder, P. K., Steffen, D. L., and Getz, M. J. (1982). Evidence for an early evolutionary origin and locus polymorphism of mouse VL30 DNA sequences. J. Virol. 43: 511-518.

Cox, D. R., Burmeister, M., Price, E. R., Kim, S., and Myers, R. M. (1990). Radiation hybrid mapping: a somatic cell genetic method for constructing high-resolution maps of mammalian chromosomes. Science 250: 245-250.

Cox, R. D., Copeland, N. G., Jenkins, N. A., and Lehrach, H. (1991). Interspersed repetitive element polymerase chain reaction product mapping using a mouse interspecific backcross. Genomics 10: 375-384.

Cox, R. D., Meier-Ewert, S., Ross, M., Larin, Z., Monaco, A. P., and Leharch, H. (1993). Genome mapping and cloning of mutations using yeast artificial chromosomes. In Guides to Techniques in Mouse Development, Methods in Enzymology 225, Wassarman, P. M. and DePamphilis, M. L., eds. (Academic Press, San Diego), pp. 623-637.

Craig, J. M., and Bickmore, W. A. (1993). Chromosome bands - flavours to savour. Bioessays 15: 349-354.

Crow, J. F. (1990). Mapping functions. Genetics 125: 669-671.

Cuénot, L. (1902). La loi de Mendel et l’hérédité de la pigmentation chez les souris. Arch. Zool. exp. gén., 3e sér. 3: 27-30.

Cuénot, L. (1903). L’hérédité de la pigmentation chez les souris, 2me note. Arch. zool. exp. gén. 4: 33-38.

Cuénot, L. (1905). Les races pures et les combinaisons chez les souris. Arch. zool. exp. gén. 4: 123-132.

Cui, X., Gerwin, J., Navidi, W., Li, H., Kuehn, M., and Arnheim, N. (1992). Gene-centromere linkage mapping by PCR analysis of individual oocytes. Genomics 13: 713-717.

D’Eustachio, P., and Clarke, V. (1993). Localization of the twitcher (twi) mutation on mouse chromosome 12. Mammal. Genome 4: 684-686.

Daniels, D. L., Plunkett, G., Burland, V., and Blattner, F. R. (1992). Analysis of the Escherichia coli genome: DNA sequence of the region from 84.5 to 86.5. Science 257: 771-777.

Davisson, M. T. (1990). The Jackson Laboratory Mouse Mutant Resource. Lab Animal 19: 23.

Davisson, M. T. (1993). Personal communication.

Davisson, M. T., and Akeson, E. C. (1993). Recombination suppression by heterozygous Robertsonian chromosomes in the mouse. Genetics 133: 649-667.

Davisson, M. T., and Roderick, T. H. (1989). Linkage map. In Genetic Variants and Strains of the Laboratory Mouse., Lyon, M. F. and Searle, A. G., eds. (Oxford University Press, Oxford), pp. 416-427.

Davisson, M. T., Roderick, T. H., and Doolittle, D. P. (1989). Recombination percentages and chromosomal assignments. In Genetic Variants and Strains of the Laboratory Mouse., Lyon, M. F. and Searle, A. G., eds. (Oxford University Press, Oxford), pp. 432-505.

Dayhoff, M. O. (1978). Survey of new data and computer methods of analysis. In Atlas of Protein Sequence and Structure, 5, supp. 3, Dayhoff, M. O., eds. (National Biomedical Research Foundation, Silver Springs, MD), pp. 2-8.

de Boer, P., and Groen, A. (1974). Fertility and meiotic behavior of male T70H tertiary trisomics of the mouse (Mus musculus). A case of preferential telomeric meiotic pairing in a mammal. Cytogenet. Cell Genet. 13: 489-510.

DeChiara, T. M., Robertson, E. J., and Efstratiadis, A. (1991). Parental imprinting of the mouse Insulin-like growth factor II gene. Cell 64: 849-859.

Demant, P., and Hart, A. A. M. (1986). Recombinant congenic strains — a new tool for analyzing genetic traits determined by more than one gene. Immunogenetics 24: 416-422.

den Dunnen, J. T., and van Ommen, G.-J. B. (1991). Pulsed-field gel electrophoresis. In Protocols in Human Molecular Genetics, Methods in Molecular Biology 9, Mathew, C. G., eds. (Humana Press, Clifton, NJ), pp. 169-182.

Dietrich, W., Katz, H., Lincoln, S., Shin, H.-S., Friedman, J., Dracopoli, N. C., and Lander, E. (1992). A genetic map of the mouse suitable for typing intraspecific crosses. Genetics 131: 423-447.

Dobrovolskaia-Zavadskaia, N. (1927). Sur la mortification spontanée de la queue chez la souris nouveau-née et sur l’existence d’un caractère (facteur) héréditaire <<non viable>>. C. r. Séanc. Soc. Biol. 97: 114-116.

Donehower, L. A., Harvey, M., Slagle, B. L., McArthur, M. J., Montgomery Jr., C. A., Butel, J. S., and Bradley, A. (1992). Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 356: 215-221.

Donis-Keller, H., Green, P., Helms, C., Cartinhour, S., Weiffenbach, B., Stephens, K., Keith, T., Bowden, D., Smith, D., Lander, E., Botstein, D., Akots, G., Rediker, K., Gravius, T., Brown, V., Rising, M., Parker, C., Powers, J., Watt, D., Kauffman, E., Bricker, A., Phipps, P., Muller-Kahle, H., Fulton, T., Ng, S., Schumm, J., Braman, J., Knowlton, R., Barker, D., Crooks, S., Lincoln, S., Daly, M., and Abrahamson, J. (1987). A genetic linkage map of the human genome. Cell 51: 319-337.

Dover, G. (1982). Molecular drive: a cohesive mode of species evolution. Nature 299: 111-117.

Drouet, B., and Simon-Chazottes, D. (1993). The microsatellite found in the DNA sequence with the code name MMMYOGG1 (GenBank) does not correspond to the myogenin gene (Myog) but to myoglobin (Mb) and maps to mouse Chromosome 15. Mammal. Genome 4: 348.

Dunn, L. C. (1965). A Short History of Genetics. (McGraw-Hill, New York).

Eddy, E. M., O’Brien, D. A., and Welch, J. E. (1991). Mammalian sperm development in vivo and in vitro. In Elements of Mammalian Fertilization, Vol. 1, Wassarman, P. M., eds. (CRC Press, Boston), pp. 1-28.

Eicher, E. M. (1971). The identification of the chromosome bearing linkage group XII in the mouse. Genetics 69: 267-271.

Eicher, E. M. (1978). Murine ovarian teratomas and parthenotes as cytogenetic tools. Cytogenet. Cell Genet. 20: 232-239.

Eicher, E. M., and Shown, E. P. (1993). Molecular markers that define the distal ends of mouse autosomes 4, 13, and 19 and the sex chromosomes. Mammal. Genome 4: 226-229.

Elliott, R. (1979). Mouse variants studied by two-dimensional electrophoresis. Mouse News Lett 61: 59.

Elliott, R. W., and Yen, C.-H. (1991). DNA variants with telomere probe enable genetic mapping of ends of mouse chromosomes. Mammal. Genome 1: 118-122.

Elston, R. C., and Stewart, J. (1971). A general model for the genetic analysis of pedigree data. Hum. Hered. 21: 523-542.

Ephrussi, B., and Weiss, M. C. (1969). Hybrid somatic cells. Scient. Amer. 220 (April): 26-34.

Eppig, J. T., and Eicher, E. M. (1983). Application of the ovarian teratoma mapping method in the mouse. Cytogenet. Cell Genet. 20: 232-239.

Eppig, J. T., and Eicher, E. M. (1988). Analysis of recombination in the centromere region of mouse chromosome 7 using ovarian teratoma and backcross methods. J. Hered. 79: 425-429.

Erickson, R. P. (1989). Why isn’t a mouse more like a man. Trend. Genet. 5: 1-3.

Erlich, H. A., eds. (1989). PCR Technology (Stockton Press, New York).

Evans, E. P. (1989). Standard Normal Chromosomes. In Genetic Variants and Strains of the laboratory mouse., Lyon, M. F. and Searle, A. G., eds. (Oxford University Press, Oxford), pp. 576-581.

Farr, C. J. (1991). The analysis of point mutations using synthetic oligonucleotide probes. In Protocols in Human Molecular Genetics, Methods in Molecular Biology 9, Mathew, C., eds. (Humana Press, Clifton, NJ), pp. 69-84.

Farr, C. J., and Goodfellow, P. N. (1992). Hidden messages in genetic maps. Science 258: 49.

Feingold, M. (1980). Preface. In Josephine: The Mouse Singer (A Play), McClure, M., eds. (New Directions Books, New York),

Ferguson-Smith, A. C., Reik, W., and Surani, M. A. (1990). Genomic imprinting and cancer. Cancer Surv. 9: 487-503.

Ferris, S. D., Sage, R. D., Huang, C.-M., Nielson, J. T., Ritte, U., and Wilson, A. C. (1983a). Flow of mitochondrial DNA across a species boundary. Proc. Nat. Acad. Sci. USA 80: 2290-2294.

Ferris, S. D., Sage, R. D., Prager, E. M., Titte, U., and Wilson, A. C. (1983b). Mitochondrial DNA evolution in mice. Genetics 105: 681-721.

Ferris, S. D., Sage, R. D., and Wilson, A. C. (1982). Evidence from mtDNA sequences that common laboratory strains of inbred mice are descended from a single female. Nature 295: 163-165.

Field, K. G., Olsen, G. J., Lane, D. J., Giovannoni, S. J., Ghiselin, M. T., Raff, E. C., Pace, N. R., and Raff, R. A. (1988). Molecular phylogeny of the animal kingdom. Science 239: 748-753.

Fiering, S., Kim, C. G., Epner, E. M., and Groudine, M. (1993). An "in-out" strategy using gene targeting and FLP recombinase for the functional dissection of complex DNA regulatory elements: analysis of the b-globin locus control region. Proc Natl Acad Sci USA 90: 8469-8473.

Fischer, S. G., and Lerman, L. S. (1983). DNA fragments differing by single-base pair substitutions are separated in denaturing gradient gels: Correspondence with melting theory. Proc. Nat. Acad. Sci. USA 80: 1579-1583.

Fisher, R. A. (1936). Has Mendel’s work been rediscovered? Annals of Science 1: 115-137.

Fitzgerald, J., Wilcox, S. A., Graves, J. A. M., and Dahl, H.-H. M. (1993). A eutherian X-linked gene, PDHA1, is autosomal in marsupials: A model for the evolution of a second, testis-specific variant in eutherian mammals. Genomics 18: 636-642.

Flaherty, L. (1981). Congenic strains. In The Mouse in Biomedical Research, Vol. 1, Foster, H. L., Small, J. D., and Fox, J. G., eds. (Academic Press, N.Y.), pp. 215-222.

Foote, S., Vollrath, D., Hilton, A., and Page, D. C. (1992). The human Y chromosome: overlapping DNA clones spanning the euchromatic region. Science 258: 60-66.

Forrest, S. (1993). Genetic algorithims: principles of natural selection applied to computation. Science 261: 872-878.

Frankel, W. N., Lee, B. K., Sotye, J. P., Coffin, J. M., and Eicher, E. M. (1992). Characterization of the endogenous nonecotropic murine leukemia viruses of NZB/BINJ and SM/J inbred strains. Mammal. Genome 2: 110-122.

Frankel, W. N., Stoye, J. P., Taylor, B. A., and Coffin, J. M. (1990). A genetic linkage map of endogenous murine leukemia proviruses. Genetics 124: 221-236.

Friedrich, G., and Soriano, P. (1991). Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev 5: 1513-23.

Gall, J. G., and Pardue, M. L. (1969). Formation and detection of RNA-DNA hybrid molecules in cytological preparations. Proc. Nat. Acad. Sci. 63: 378-382.

Gardner, M. B., Kozak, C. A., and O’Brien, S. J. (1991). The Lake Casitas wild mouse: evolving genetic resistance to retroviral disease. Trend Genet. 7: 22-27.

Garrels, J. I. (1983). Quantitative two-dimensional gel electrophoresis of proteins. Methods Enzymol 100: 411-423.

Gasser, D. L., Sternberg, N. L., Pierce, J. C., Goldner, S. A., Feng, H., Haq, A. K., Spies, T., Hunt, C., Buetow, K. H., and Chaplin, D. D. (1994). P1 and cosmid clones define the organization of 280 kb of the mouse H-2 complex containing the Cps-1 and Hsp70 loci. Immunogenetics 39: 48-55.

Geliebter, J., and Nathenson, S. G. (1987). Recombination and the concerted evolution of the murine MHC. Trends Genet 3: 107-112.

Gendron-Maguire, M., and Gridley, T. (1993). Identification of transgenic mice. In Guides to Techniques in Mouse Development, Methods in Enzymology 225, Wassarman, P. M. and DePamphilis, M. L., eds. (Academic Press, San Diego), pp. 794-799.

Giacalone, J., Friedes, J., and Francke, U. (1992). A novel GC-rich human macrosatellite VNTR in Xq24 is differentially methylated on active and inactive X chromosomes. Nature Genetics 1: 137-143.

Goradia, T. M., Stanton, V. P., Cui, X., Aburatani, H., Li, H., Lange, K., Housman, D. E., and Arnheim, N. (1991). Ordering three DNA polymorphisms on human chromosome 3 by sperm typing. Genomics 10: 748-755.

Gordon, J. W., and Ruddle, F. H. (1981). Integration and stable germ line transmission of genes injected into mouse pronuclei. Science 214: 1244-1246.

Gossler, A., Joyner, A. L., Rossant, J., and Skarnes, W. C. (1989). Mouse embryonic stem cells and reporter constructs to detect developmentally regulated genes. Science 244: 463-5.

Graff, R. J. (1978). Minor histocompatibility genes and their antigens. In Origins of Inbred Mice, Morse, H. C., eds. (Academic Press, New York), pp. 371-389.

Graur, D., Hide, W. A., and Li, W.-H. (1991). Is the guinea-pig a rodent? Nature 351: 649-652.

Gray, J. W., Dean, P. N., Fuscoe, J. C., Peters, D. C., and Trask, B. J. (1990). High-speed chromosome sorting. Science 238: 323-329.

Green, E. D., and Olson, M. V. (1990). Systematic screening of yeast artificial-chromosome libraries by use of the polymerase chain reaction. Proc. Nat. Acad. Sci. USA 87: 1213-1217.

Green, E. L. (1981). Genetics and Probability in Animal Breeding Experiments. (Oxford University Press, New York).

Green, E. L., and Roderick, T. H. (1966). Radiation Genetics. In Biology of the Laboratory Mouse, Green, E. L., eds. (McGraw-Hill, New York), pp. 165-185.

Green, M. C. (1966). Mutant genes and linkages. In Biology of the Laboratory Mouse, Green, E. L., eds. (McGraw-Hill, New York), pp. 87-150.

Green, M. C. (1989). Catalog of mutant genes and polymorphic loci. In Genetic Variants and Strains of the Laboratory Mouse, Lyon, M. F. and Searle, A. G., eds. (Oxford University Press, Oxford), pp. 12-403.

Green, M. C., and Witham, B. A., eds. (1991). Handbook on Genetically Standardized JAX Mice fourth edition (The Jackson Laboratory, Bar Harbor).

Gropp, A., Winking, H., Zech, L., and Muller, H. (1972). Robertsonian chromosomal variation and identification of metacentric chromosomes in feral mice. Chromosoma 39: 265-288.

Grosveld, F., Blom van Assendelft, G., Greaves, D. R., and Kollias, G. (1987). Position-independent, high-level expression of the human b-globin gene in transgenic mice. Cell 51: 975-985.

Grüneberg, H. (1943). The Genetics of the Mouse. (Cambridge University Press, Cambridge).

Guenet, J.-L., Nagamine, C., Simon-Chazottes, D., Montagutelli, X., and Bonhomme, F. (1990). Hst3: an X-linked hybrid sterility gene. Genet Res Camb 56: 163.

Gyllensten, U., and Wilson, A. C. (1987). Interspecific mitochondrial DNA transfer and the colonization of Scandinavia by mice. Genet. Res. Camb. 49: 25-29.

Hagag, N. G., and Viola, M. V. (1993). Chromosome microdissection and cloning. (Academic Press, San Diego).

Haig, D., and Graham, C. (1991). Genomic imprinting and the strange case of the insulin-like growth factor II receptor. Cell 64: 1045-1046.

Haldane, J. B. S. (1919). The mapping function. J. Genet. 8: 299-309.

Haldane, J. B. S. (1922). Sex ratio and unisexual sterility in hybrid animals. J. Genetics 12: 101-109.

Haldane, J. B. S., Sprunt, A. D., and Haldane, N. M. (1915). Reduplication in mice. J. Genet. 5: 133-135.

Haldane, J. B. S., and Waddington, C. H. (1931). Inbreeding and linkage. Genetics 16: 357-374.

Hamada, H., and Kakunaga, T. (1982). Potential Z-DNA forming sequences are highly dispersed in the human genome. Nature 298: 396-398.

Hamada, H., Petrino, M. G., and Kakunaga, T. (1982). A novel repeated element with Z-DNA-forming potential is widely found in evolutionarily diverse eukaryotic genomes. Proc Natl Acad Sci USA 79: 6465-6469.

Hammer, M. F., Bliss, S., and Silver, L. M. (1991). Genetic exchange across a paracentric inversion of the mouse t complex. Genetics 128: 799-812.

Hammer, M. F., Schimenti, J., and Silver, L. M. (1989). Evolution of mouse chromosome 17 and the origin of inversions associated with t haplotypes. Proc Natl Acad Sci U S A 86: 3261-5.

Hanscombe, O., Whyatt, D., Fraser, P., Yannoutsos, N., Greaves, D., Dillon, N., and Grosveld, F. (1991). Importance of globin gene order for correct developmental expression. Genes Develop 5: 1387-1394.

Harbers, K., Jahner, D., and Jaenisch, R. (1981). Microinjection of cloned retroviral genomes into mouse zygotes: Integration and expression in the animal. Nature 293: 540-542.

Harding, R. M., Boyce, A. J., and Clegg, J. B. (1992). The evolution of tandemly repetitive DNA: recombination rules. Genetics 132: 847-859.

Harper, M. E., Ullrich, A., and Saunders, G. F. (1981). Localization of the human insulin gene to the distal end of the short arm of chromosome 11. Proc Natl Acad Sci USA 78: 4458-4460.

Hasties, N. D. (1989). Highly repeated DNA families in the genome of Mus musculus. In Genetic Variants and Strains of the Laboratory Mouse., Lyon, M. F. and Searle, A. G., eds. (Oxford University Press, Oxford), pp. 559-573.

Hasties, N. D., and Bishop, J. O. (1976). The expression of three abundance classes of messenger RNA in mouse tissues. Cell 9: 761-774.

Hasty, P., Ramirez-Solis, R., Krumlauf, R., and Bradley, A. (1991). Introduction of a subtle mutation into the Hox 2.6 locus in embryonic stem cells. Nature 351: 234-246.

Hatada, I., Hayashizaki, Y., Hirotsune, S., Komatsubara, H., and Mukai, T. (1991). A genomic scanning method for higher organisms using restriction sites as landmarks. Proc Natl Acad Sci U S A 88: 9523-7.

Hearne, C. M., Ghosh, S., and Todd, J. A. (1992). Microsatellites for linkage analysis of genetic traits. Trends Genet. 8: 288-294.

Helmuth, R. (1990). Nonisotopic detection of PCR products. In PCR protocols, Innis, M. A., Gelfand, D. H., Sninsky, J. J., and White, T. J., eds. (Academic Press, San Diego), pp. 119-128.

Henry, I., Bonaiti-Pellie, C., Chehensse, V., Beldjord, C., Schwartz, C., Utermann, G., and Junien, C. (1991). Uniparental paternal disomy in a genetic cancer-predisposing syndrome. Nature 351: 665-667.

Henson, V., Palmer, L., Banks, S., Nadeau, J. H., and Carlson, G. A. (1991). Loss of heterozygosity and mitotic linkage maps in the mouse. Proc. Nat. Acad. Sci. 88: 6486-6490.

Herman, G. E., Berry, M., Munro, E., Craig, I. W., and Levy, E. R. (1991). The construction of human somatic cell hybrids containing portions of the mouse X chromosome and their use to generate DNA probes via interspersed repetitive sequence polymerase chain reaction. Genomics 10: 961-970.

Herman, G. E., Nadeau, J. H., and Hardies, S. C. (1992). Dispersed repetitive elements in mouse genome analysis. Mammal. Genome 2: 207-214.

Herrmann, B. G., Barlow, D. P., and Lehrach, H. (1987). A large inverted duplication allows homologous recombination between chromosomes heterozygous for the proximal t complex inversion. Cell 48: 813-825.

Hillyard, A. L., Doolittle, D. P., Davisson, M. T., and Roderick, T. H. (1992). Locus map of the mouse. Mouse Genome 90: 8-21.

Himmelbauer, H., and Silver, L. M. (1993). High resolution comparative mapping of mouse chromosome 17. Genomics 17: 110-120.

Hochgeschwender, U. (1992). Toward a transcriptional map of the human genome. Trends Genet 8: 41-44.

Hogan, B., Beddington, R., Costantini, F., and Lacy, E. (1994). Manipulating the Mouse Embryo: A Laboratory Manual, Second Edition. (Cold Spring Harbor Laboratory Press, Cold Spring Harbor).

Hood, L. (1992). Personal communication.

Hood, L., Kronenberg, M., and Hunkapiller, T. (1985). T cell antigen receptors and the immunoglobulin supergene family. Cell 40: 225-229.

Horiuchi, Y., Agulnik, A., Figueroa, F., Tichy, H., and Klein, J. (1992). Polymorphisms distinguishing different mouse species and t haplotypes. Genet. Res. 60: 43-52.

Hörz, W., and Altenburger, W. (1981). Nucleotide sequence of mouse satellite DNA. Nucl. Acids Res. 9: 683-696.

Huntington’s Disease Collaborative Research Group (1993). A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington’s disease chromosomes. Cell 72: 971-983.

Huxley, A. (1932). Brave New World. (Doubleday, Doran & Co., Garden City, NY).

Innis, M. A., Gelfand, D. H., Sninsky, J. J., and White, T. J., eds. (1990). PCR protocols (Academic Press, San Diego).

Jaeger, J.-J., Tong, H., and Denys, C. (1986). The age of Mus-Rattus divergence: paleontological data compared with the molecular clock. C.R. Acad. Sci. Paris 302 (ser. II): 917-922.

Jaenisch, R. (1976). Germ line integration and Mendelian transmission of the exogenous Molony leukemia virus. Proc. Nat. Acad. Sci. 73: 1260-1264.

Jahn, C. L., Hutchison, C. A., Phillips, S. J., Weaver, S., Haigwood, N. L., Voliva, C. F., and Edgell, M. H. (1980). DNA sequence organization of the beta-globin complex in the BALB/c mouse. Cell 21: 159-168.

Jakobovits, A., Moore, A. L., Green, L. L., Vergara, G. J., Maynard-Currie, C. E., Austin, H. A., and Klapholz, S. (1993). Germ-line transmission and expression of a human-derived yeast artificial chromosome. Nature 362: 255-258.

Jan, Y. N., and Jan, L. Y. (1993). Functional gene cassettes in development. Proc Natl Acad Sci USA 90: 8305-8307.

Jarman, A. P., and Wells, R. A. (1989). Hypervariable minisatellites: recombinations or innocent bystanders? Trends Genet 5: 367-371.

Jeang, K. T., and Hayward, G. S. (1983). A cytomegalovirus DNA sequence containing tracts of tandemly repeated CA dinucleotides hybridizes to highly repetitive dispersed elements in mammalian cell genomes. Mol. Cell. Biol. 3: 1389.

Jeffreys, A. J., Royle, N. J., Wilson, V., and Wong, Z. (1988). Spontaneous mutation rates to new length alleles at tandem-repetitive hypervariable loci in human DNA. Nature 332: 278-281.

Jeffreys, A. J., Wilson, V., Kelly, R., Tayor, B. A., and Bulfield, G. (1987). Mouse DNA "fingerprints": Analysis of chromosome localization and germ-line stability of hypervariable loci in recombinant inbred strains. Nucl Acids Res 15: 2823-2836.

Jeffreys, A. J., Wilson, V., and Thein, S. L. (1985). Individual-specific ‘fingerprints’ of human DNA. Nature 316: 76-79.

Jenkins, N. A., and Copeland, N. G. (1985). High frequency germline acquisition of ecotropic MuLV proviruses in SWR/J-RF/J hybrid mice. Cell 43: 811-819.

Jenkins, N. A., Copeland, N. G., Taylor, B. A., and Lee, B. K. (1982). Organization, distribution, and stability of endogenous ecotropic murine leukemia virus DNA sequences in chromosomes of Mus musculus. J. Virol. 43: 26-36.

John, H., Birnstiel, M. L., and Jones, K. N. (1969). RNA-DNA hybrids at the cytological level. Nature 223: 582-585.

Johnson, D. R. (1974). Hairpin-Tail: a case of post-reductional gene action in the mouse egg? Genetics 76: 795-805.

Joyner, A., eds. (1993). Gene targeting: A practical approach (Oxford University Press, New York).

Joyner, A. L., Auerbach, A., and Skarnes, W. C. (1992). The gene trap approach in embryonic stem cells: the potential for genetic screens in mice. Ciba Found Symp 165: 277-88.

Joyner, A. L., Skarnes, W. C., and Rossant, J. (1989). Production of a mutation in the mouse En-2 gene by homologous recombination in embryonic stem cells. Nature 338: 153-156.

Julier, C., DeGouyon, B., Georges, M., Guenet, J.-L., Nakamura, Y., and Avner, P. (1990). Minisatellite linkage maps in the mouse by cross-hybridization with human probes containing tandem repeats. Proc. Nat. Acad. Sci. USA 87: 4585-4589.

Kasahara, M., Figueroa, F., and Klein, J. (1987). Random cloning of genes from mouse chromosome 17. Proc. Natl. Acad. Sci. U.S.A. 84: 3325-3328.

Keeler, C. E. (1931). The Laboratory Mouse. Its Origin, Heredity, and Culture. (Harvard University Press, Cambridge).

Kerr, R. (1991). Extinction potpourri: Killers and victims. Science 254: 942-943.

Kerr, R. A. (1992). Extinction by a one-two comet punch? Science 255: 160-161.

Kerr, R. A. (1993). Second Crater Points to Killer Comets. Science 259: 1543.

Keshet, E., and Itin, A. (1982). Patterns of genomic distribution and sequence heterogeneity of a murine "retrovirus-like" multigene family. J. Virol. 43: 50-58.

Kevles, D. J., and Hood, L., eds. (1992). The Code of Codes: Scientific and Social Issues in the Human Genome Project (Harvard University Press, Boston).

Kidd, S., Lockett, T. J., and Young, M. W. (1983). The notch locus of Drosophila melanogaster. Cell 34: 421-433.

King, T. R., Dove, W. F., Herrmann, B., Moser, A. R., and Shedlovsky, A. (1989). Mapping to molecular resolution in the T to H-2 region of the mouse genome with a nested set of meiotic recombinants. Proc. Natl. Acad. Sci. USA 86: 222-226.

Kingsley, D. M., Bland, A. E., Grubber, J. M., Marker, P. C., Russell, L. B., Copeland, N. G., and Jenkins, N. A. (1992). The mouse short ear skeletal morphogenesis locus is associated with defects in a bone morphogenetic member of the TGFbeta superfamily. Cell 71: 399-410.

Kit, S. (1961). Equilibrium sedimentation in density gradients of DNA preparations from animal tissues. J. Mol. Biol. 3: 711-716.

Klein, J. (1986). Natural History of the Major Histocompatibility Complex. (John Wiley & Sons, New York).

Knight, A. M., and Dyson, P. J. (1990). Detection of DNA polymorphisms between two inbred mouse strains--limitations of restriction fragment length polymorphisms (RFLPs). Mol Cell Probes 4: 497-504.

Korenberg, J. R., and Rykowski, M. C. (1988). Human genome organization: Alu, Lines, and the molecular structure of metaphase chromosome bands. Cell 53: 391-400.

Kosambi, D. D. (1944). The estimation of map distances from recombination values. Ann. Eugenics 12: 172-175.

Kozak, C., Peters, G., Pauley, R., Morris, V., Michalides, R., Dudley, J., and others (1987). A standardized nomenclature for endogenous mouse mammary tumor viruses. J. Virol. 61: 1651-1654.

Kramer, J. M., and Erickson, R. P. (1981). Developmental program of PGK-1 and PGK-2 isozymes in spermatogenic cells of the mouse: Specific activities and rates of synthesis. Dev. Biol. 87: 37-45.

Kunkel, L. M., Monaco, A. P., Middlesworth, W., Ochs, H. D., and Latt, S. A. (1985). Specific cloning of DNA fragments absent from the DNA of a male patient with an X-chromosome deletion. Proc. Nat. Acad. Sci. USA 82: 4778-4782.

Kusumi, K., Smith, J. S., Segre, J. A., Koos, D. S., and Lander, E. S. (1993). Construction of a large-insert yeast artificial chromosome library of the mouse genome. Mammal. Genome 4: 391-392.

Kwiatkowski, D. J., Dib, C., Slaugenhaupt, S. A., Povey, S., Gusella, J. F., and Haines, J. L. (1993). An index marker map of chromosome 9 provides strong evidence for positive interference. Am. J. Hum. Genet. 53: 1279-1288.

Laird, C. D. (1971). Chromatid structure: relationship between DNA content and nucleotide sequence diversity. Chromosoma 32: 378-406.

Landegren, U., Kaiser, R., and Hood, L. (1990). Oligonucleotide ligation assay. In PCR Protocols, Innis, M. A., Gelfand, D. H., Sninsky, J. J., and White, T. J., eds. (Academic Press, San Diego), pp. 92-98.

Landegren, U., Kaiser, R., Sanders, J., and Hood, L. (1988). A ligase-mediated gene detection technique. Science 241: 1077-1080.

Lander, E. S., Green, P., Abrahamson, J., Barlow, A., Daly, M. J., Lincoln, S. E., and Newburg, L. (1987). MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations. Genomics 1: 174-81.

Larin, Z., Monaco, A. P., and Lehrach, H. (1991). Yeast artificial chromosome libraries containing large inserts from mouse and human DNA. Proc Natl Acad Sci U S A 88: 4123-7.

Larin, Z., Monaco, A. P., Meier-Ewert, S., and Leharch, H. (1993). Construction and characterization of yeast artificial chromosome libraries from the mouse genome. In Guides to Techniques in Mouse Development, Methods in Enzymology 225, Wassarman, P. M. and DePamphilis, M. L., eds. (Academic Press, San Diego), pp. 623-637.

Laurie, D. A., and Hulten, M. A. (1985). Further studies on chiasma distribution and interference in the human male. Ann. Hum. Genet. 49: 203-214.

Lawrence, J. B. (1990). A fluorescence in situ hybridization approach for gene mapping and the study of nuclear organization. In Genetic and Physical Mapping, Genome Analysis 1, Davies, K. E. and Tilghman, S., eds. (Cold Spring Harbor Laboratory Press,

Leder, A., Swan, D., Ruddle, F., D’Eustachio, P., and Leder, P. (1981). Dispersion of alpha-like globin genes of the mouse to three different chromosomes. Nature 293: 196-200.

LeRoy, H., Simon-Chazottes, D., Montagutelli, X., and Guénet, J.-L. (1992). A set of anonymous DNA clones as markers for mouse gene mapping. Mammal. Genome 3: 244-246.

Levenson, C., and Chang, C.-a. (1990). Nonisotopically labelled probes and primers. In PCR protocols, Innis, M. A., Gelfand, D. H., Sninsky, J. J., and White, T. J., eds. (Academic Press, San Diego), pp. 99-112.

Li, H., Gyllensten, U. B., Cui, X., Saiki, R. K., Erlich, H. A., and Arnheim, N. (1988). Amplification and analysis of DNA sequences in single human sperm and diploid cells. Nature 335: 414-417.

Lindsay, S., and Bird, A. P. (1987). Use of restriction enzymes to detect potential gene sequences in mammalian DNA. Nature 327: 336-338.

Lisitsyn, N., Lisitsyn, N., and Wigler, M. (1993). Cloning the differences between two complex genomes. Science 259: 946-951.

Lister, C., and Dean, C. (1993). Recombinant inbred lines for mapping RFLP and phenotypic markers in Arabidopsis thaliana. The Plant Journal 4: 745-750.

Little, C. C., and Bagg, H. J. (1924). The occurrence of four inheritable morphological variations in mice and their possible relation to treatment with X-rays. J. Exp. Zool. 41: 45-92.

Little, P. (1993). The end of the beginning. Nature 362: 408-409.

Love, J. M., Knight, A. M., McAleer, M. A., and Todd, J. A. (1990). Towards construction of a high resolution map of the mouse genome using PCR-analyzed microsatellites. Nuc. Acids Res. 18: 4123-4130.

Lovett, M., Kere, J., and Hinton, L. M. (1991). Direct selection: A method for the isolation of cDNAs encoded by large genomic regions. Proc. Nat. Acad. Sci. 88: 9628-9632.

Lowe, T., Sharefkin, J., Yang, S.-Q., and Dieffenbach, C. W. (1990). A computer program for selection of oligonucleotide primers for polymerase chain reactions. Nucleic Acids Res 18: 1757-1761.

Ludecke, H.-J., Senger, G., Claussen, U., and Horsthemke, B. (1989). Cloning defined regions of the human genome by microdissection of banded chromosomes and enzymatic amplification. Nature 338: 348-350.

Lueders, K. K., and Kuff, E. L. (1977). Sequences associated with intracisternal A-particles are reiterated in the mouse genome. Cell 12: 963-972.

Lyon, M. F., and Kirby, M. C. (1992). Mouse chromosome atlas. Mouse Genome 90: 22-44.

Lyon, M. F., and Searle, A. G., eds. (1989). Genetic Variants and Strains of the Laboratory Mouse. 2nd (Oxford University Press, Oxford).

Maniatis, T., Fritsch, E. F., and Sambrook, J. (1982). Molecular Cloning: A Laboratory Manual. (Cold Spring Harbor Laboratory, Cold Spring Harbor, NY).

Manly, K. F. (1993). A macintosh program for storage and analysis of experimental genetic mapping data. Mammal. Genome 4: 303-313.

Marchuk, D. A., and Collins, F. S. (1994). The use of YACs to identify expressed sequences: cDNA screening using total YAC insert. In YAC Libraries, A User’s Guide, Nelson, D. L. and Brownstein, B. H., eds. (W.H. Freeman and Company, New York),

Mariat, D., and Vergnaud, G. (1992). Detection of polymorphic loci in complex genomes with synthetic tandem repeats. Genomics 12: 454-458.

Marshall, C. J. (1991). Tumor suppressor genes. Cell 64: 313.

Marshall, J. D., Mu, J.-L., Nesbitt, M. N., Frankel, W. N., and Paigen, B. (1992). The AXB and BXA set of recombinant inbred mouse strains. Mammal. Genome 3: 669-680.

Marshall, J. T. (1981). Taxonomy. In The Mouse in Biomedical Research, Vol. 1, Foster, H. L., Small, J. D., and Fox, J. G., eds. (Academic Press, N.Y.), pp. 17-26.

Martin, G. B., Brommonschenkel, S. H., Chunwongse, J., Frary, A., Ganal, M. W., Spivey, R., Wu, T., Earle, E. D., and Tanksley, S. D. (1993). Map-based cloning of a protein kinase gene conferring disease resistance in tomato. Science 262: 1432-1436.

Martin, S. L. (1991). LINEs. Curr. Opin. Genet. Develop. 1: 505-508.

Matsuda, Y., and Chapman, V. M. (1991). In situ analysis of centromeric satellite DNA segregating in Mus species crosses. Mammal. Genome 1: 71-77.

Matsuda, Y., Manly, K. F., and Chapman, V. M. (1993). In situ analysis of centromere segregation in C57BL/6 X Mus spretus interspecific backcrosses. Mammal. Genome 4: 475-480.

McClelland, M., and Ivarie, R. (1982). Asymmetrical distribution of CpG in an ‘average’ mammalian gene. Nucl. Acids Res. 10: 7865-7877.

McDonald, J. D., Shedlovsky, A., and Dove, W. F. (1990). Investigating inborn errors of phenylalanine metabolism by efficient mutagenesis of the mouse germ line. In Biology of Mammalian Germ Cell Mutagenesis, Allen, J. W., Bridges, B. A., Lyon, M. F., Moses, M. J., and Russell, L. B., eds. (Cold Spring Harbor Press, Cold Spring Harbor), pp. 259-270.

McGinnis, W., and Krumlauf, R. (1992). Homeobox genes and axial patterning. Cell 68: 283-302.

McGrath, J., and Solter, D. (1983). Nuclear Transplantation in the mouse embryo by microsurgery and cell fusion. Science 220: 1300-1302.

McKusick, V. (1988). Mendelian Inheritance in Man: Catalogs of Autosomal Dominant, Autosomal Recessive, and X-Linked Phenotypes. 8th (The Johns Hopkins University Press, Baltimore).

Meisler, M. H. (1992). Insertional mutation of ‘classical’ and novel genes in transgenic mice. Trend Genet. 8: 341-344.

Meitz, J. A., and Kuff, E. L. (1992). Intracisternal A-particle-specific oligonucleotides provide multilocus probes for genetic linkage studies in the mouse. Mammal. Genome 3: 447-451.

Michaud, J., Brody, L. C., Steel, G., Fontaine, G., Martin, L. S., Valle, D., and Mitchell, G. (1992). Strand-separating conformational polymorphism analysis: efficacy of detection of point mutations in the human ornithine d-aminotransferase gene. Genomics 13: 389-394.

Michelmore, R. W., Paran, I., and Kesseli, R. V. (1991). Identification of markers linked to disease-resistance genes by bulked segregant analysis: a rapid method to detect markers in specific genomic regions by using segregating populations. Proc Natl Acad Sci U S A 88: 9828-32.

Michiels, F., Burmeister, M., and Lehrach, H. (1987). Derivation of clones close to met by preparative field inversion gel electrophoresis. Science 236: 1305-1308.

Miesfeld, R., Krystal, M., and Arnheim, N. (1981). A member of new repeated sequence family which is conserved throughout eucaryotic evolution is found between the human delta- and beta-globin genes. Nuc. Acids Res. 9: 5931.

Miller, O. J., and Miller, D. A. (1975). Cytogenetics of the mouse. Ann. Rev. Genet. 9: 285-303.

Milner, C. M., and Campbell, R. D. (1992). Genes, genes and more genes in the human major histocompatibility complex. BioEssays 14: 565-571.

Montagutelli, X. (1990). GENE-LINK: a program in PASCAL for backcross genetic analysis. J Hered 81: 490-1.

Moore, D. S., and McCabe, G. P. (1989). Introduction to the Practice of Statistics. (W.H. Freeman & Co., New York).

Moore, T., and Haig, D. (1991). Genomic imprinting in mammalian development: A parental tug-of-war. Trends Genet 7: 45-49.

Morgan, T. H., and Cattell, E. (1912). Data for the study of sex-linked inheritance in Drosophila. J. Exp. Zool. 13: 79-101.

Morse, H. C. (1978). Introduction. In Origins of Inbred Mice, Morse, H. C., eds. (Academic Press, New York), pp. 1-31.

Morse, H. C. (1981). The laboratory mouse - A historical perspective. In The Mouse in Biomedical Research, Vol. 1, Foster, H. L., Small, J. D., and Fox, J. G., eds. (Academic Press, New York), pp. 1-16.

Morse, H. C. (1985). The Bussey Institute and the early days of mammalian genetics. Immunogenet. 21: 109-116.

Morton, N. (1955). Sequential tests for the detection of linkage. Am. J. Hum. Genet. 7: 277-318.

Moseley, W. S., and Seldin, M. F. (1989). Definition of mouse chromosome 1 and 3 gene linkage groups that are conserved on human chromosome 1: Evidence that a conserved linkage group spans the centromere of human chromosome 1. Genomics 5: 899-905.

Moulia, C., Aussel, J. P., Bonhomme, F., Boursot, P., Nielsen, J. T., and Renaud, F. (1991). Wormy mice in a hybrid zone: a genetic control of susceptibility to parasite infection. J. Evol. Biol. 4: 679-687.

Moyzis, R. K., Buckingham, J. M., Cram, L. S., Dani, M., Deaven, L. L., Jones, M. D., Meyne, J., Ratliffe, R. L., and Wu, J.-R. (1988). A highly conserved repetitive DNA sequence (TTAGGG) present at the telomeres of human chromosomes. Proc. Nat. Acad. Sci. USA 85: 6622-6626.

Mu, J. L., Naggert, J. K., Nishina, P. M., Cheach, Y. C., and Paigen, B. (1993). Strain distribution pattern in AXB and BXA recombinant inbred strains for loci on murine chromosomes 10, 13, 17, and 18. Mammal. Genome 4: 148-152.

Muller, H. J. (1916). The mechanism of crossing-over. Am. Nat. 50: 193-221.

Muller, H. J. (1927). Artificial transmutation of the gene. Science 66: 84-87.

Nadeau, J. H. (1984). Lengths of chromosomal segments conserved since divergence of man and mouse. Proc. Nat. Acad. Sci. 81: 814-818.

Nadeau, J. H., Bedigian, H. G., Bouchard, G., Denial, T., Kosowksy, M., Norberg, R., Pugh, S., Sargeant, E., Turner, R., and Paigen, B. (1992). Multilocus markers for mouse genome analysis: PCR amplification based on single primers of arbitrary nucleotide sequence. Mammal. Genome 3: 55-64.

Nadeau, J. H., Herrmann, B., Bucan, M., Burkart, D., Crosby, J. L., Erhart, M. A., Kosowsky, M., Kraus, J. P., Michiels, F., Schnattinger, A., Tchetgen, M.-B., Varnum, D., Willison, K., Lehrach, H., and Barlow, D. (1991). Genetic maps of mouse chromosome 17 including 12 new anonymous DNA loci and 25 anchor loci. Genomics 9: 78-89.

Nakamura, Y., Leppert, M., O’Connell, P., Wolff, R., Holm, T., Culver, M., Martin, C., Fujimoto, E., Hoff, M., Kumlin, E., and White, R. (1987). Variable number of tandem repeat (VNTR) markers for human gene mapping. Science 235: 1616-1622.

Nebel, B. R., Amarose, A. P., and Hackett, E. M. (1961). Calender of gametogenic development in the prepuberal male mouse. Science 134: 832-833.

Nei, M. (1987). Molecular Evolutionary Genetics. (Columbia University Press, New York).

Nelson, D. L., and Brownstein, B. H., eds. (1994). YAC Libraries, A User’s Guide (W.H. Freeman and Company, New York).

Nelson, D. L., Ledbetter, S. A., Corbo, L., Victoria, M. F., Ramirez-Solis, R., Webster, T. D., Ledbetter, D. H., and Caskey, T. (1989). Alu polymerase chain reaction: A method for rapid isolation of human-specific sequences from complex DNA sources. Proc. Nat. Acad. Sci. USA 86: 6686-6690.

Neumann, P. E. (1990). Two-locus linkage analysis using recombinant inbred strains and Bayes’ Theorem. Genetics 126: 277-284.

Neumann, P. E. (1991). Three-locus linkage analysis using recombinant inbred strains and Bayes’ theorem. Genetics 128: 631-638.

Nichols, R. D., Knoll, J. H. M., Butler, M. G., Karam, S., and Lalande, M. (1989). Genetic imprinting suggested by maternal heterodisomy in non-deletion Prader-Willi syndrome. Nature 342: 281-285.

North, M. A., Sanseau, P., and Buckler, A. J. (1993). Efficiency and specificity of gene isolation by exon amplification. Mammal. Genome 4: 466-474.

O’Brien, S., Womack, J. E., Lyons, L. A., Moore, K. J., Jenkins, N. A., and Copeland, N. G. (1993). Anchored reference loci for comparative genome mapping in mammals. Nature Genetics 3: 103-112.

O’Farrell, P. H. (1975). High resolution two-dimensional electrophoresis of proteins. J. Biol. Chem. 250: 4007-4021.

Oakberg, E. F. (1956a). A description of spermiogenesis in the mouse and its use in the analysis of the cycle of the seminiferous epithelium and germ cell renewal. Amer. J. Anat. 99: 391-413.

Oakberg, E. F. (1956b). Spermatogenesis in the mouse and timing of stages of the cycle of the seminiferous epithelium. Am. J. Anat. 99: 507-516.

Ohno, S. (1967). Sex Chromosomes and Sex-Linked Genes. (Springer Verlag, Berlin).

Okada, N. (1991). SINEs. Curr. Opin. Genet. Develop. 1: 498-504.

Olds-Clarke, P., and Peitz, B. (1985). Fertility of sperm from t/+ mice: evidence that +-bearing sperm are dysfunctional. Genet. Res. 47: 49-52.

Ollmann, M. M., Winkes, B. M., and Barsh, G. S. (1992). Construction, analysis, and application of a radiation hybrid mapping panel surrounding the mouse agouti locus. Genomics 13: 731-740.

Orita, M., Iwahana, H., Kanazawa, H., Hayashi, K., and Sekiya, T. (1989a). Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms. Proc. Nat. Acad. Sci.USA 86: 2766-2770.

Orita, M., Suzuki, Y., Sekiya, T., and Hayashi, K. (1989b). Rapid and sensitive detection of point mutations and DNA polymorphims using the polymerase chain reaction. Genomics 5: 874-879.

Painter (1928). Genetics 13: 180-189.

Palmiter, R. D., and Brinster, R. L. (1986). Germ-line transformation of mice. Ann. Rev. Genet. 20: 465-499.

Papaioannou, V. E., and Festing, M. F. W. (1980). Genetic drift in a stock of laboratory mice. Labortory Animals 14: 11-13.

Pardue, M. L., and Gall, J. G. (1970). Chromosomal localization of mouse satellite DNA. Science 168: 1356-1358.

Parimoo, S., Patanjali, S. R., Shukla, H., Chaplin, D. D., and Weissman, S. M. (1991). cDNA selection: Efficient PCR approach for the selection of cDNAs encoded in large chromosomal DNA fragments. Proc. Nat. Acad. Sci. 88: 9623-9627.

Parrish, J. E., and Nelson, D. L. (1993). Methods for finding genes: a major rate-limiting step in positional cloning. Gen. Anal. Tech. Appl. 10: 29-41.

Patanjali, S. R., Parimoo, S., and Weismann, S. M. (1991). Construction of a uniform abundance (normalized) cDNA library. Proc. Nat. Acad. Sci. USA 88: 1943-1947.

Pedersen, R. A., Papaioannou, V., Joyner, A., and Rossant, J. (1993). Targeted Mutagenesis in Mice. Audiovisual material from Cold Spring Harbor Laboratory Press, Cold Spring Harbor.

Pickford, I. (1989) Ph.D. thesis, Imperial Cancer Research Foundation.

Pierce, J. C., Sternberg, N., and Sauer, B. (1992). A mouse genomic library in the bacteriophage P1 cloning system: organization and characterization. Mamm Genome 3: 550-8.

Pierce, J. C., and Sternberg, N. L. (1992). Using bacteriophage P1 system to clone high molecular weight genomic DNA. Methods Enzymol 216: 549-74.

Popp, R. A., Bailiff, E. G., Skow, L. C., Johnson, F. M., and Lewis, S. E. (1983). Analysis of a mouse alpha-globin gene mutation induced by ethylnitrosourea. Genetics 105: 157-167.

Potter, M., Nadeau, J. H., and Cancro, M. P., eds. (1986). The Wild Mouse in Immunology (Springer-Verlag, New York).

Povey, S., Smith, M., Haines, J., Kwiatkowski, D., Fountain, J., Bale, A., Abbott, C., Jackson, I., Lawrie, M., and Hultén, M. (1992). Report on the first international workshop on chromosome 9. Ann. Hum. Genet. 56: 167-221.

Punnett, R. C. (1911). Mendelism. (Macmillan, New York).

Rajan, T. V., Halay, E. D., Potter, T. A., Evans, G. A., Seidman, J. G., and Margulies, D. H. (1983). H-2 hemizygous mutants from a heterozygous cell line: Role of mitotic recombination. EMBO J 2: 1537-1542.

Rattner, J. B. (1991). The structure of the mammalian centromere. Bioessays 13: 51-56.

Reeves, R. H., Crowley, M. R., Moseley, W. S., and Seldin, M. F. (1991). Comparison of interspecific to intersubspecific backcrosses demonstrates species and sex differences in recombination frequency on mouse chromosome 16. Mammal. Genome 1: 158-164.

Ridley, R. M., Frith, C. D., Farrer, L. A., and Conneally, P. M. (1991). Patterns of inheritance of the symptoms of Huntington disease suggestive of an effect of genomic imprinting. J. Med. Genet. 28: 224-231.

Rikke, B. A., Garvin, L. D., and Hardies, S. C. (1991). Systematic identification of LINE-1 repetitive DNA sequence differences having species specificity between Mus spretus and Mus domesticus. J Mol Biol 219: 635-643.

Rikke, B. A., and Hardies, S. C. (1991). LINE-1 repetitive DNA probes for species-specific cloning from Mus spretus and Mus domesticus genomes. Genomics 11: 895-904.

Riley, J., Butler, R., Ogilvie, D., Finniear, R., Jenner, D., Powell, S., Anand, R., Smith, J. C., and Markham, A. F. (1990). A novel rapid method for the isolation of terminal sequences from yeast artificial chromosome (YAC) clones. Nucl. Acid Res. 18: 2887-2890.

Rinchik, E. M. (1991). Chemical mutagenesis and fine-structure functional analysis of the mouse genome. Trend. Genet. 7: 15-21.

Rinchik, E. M., Bangham, J. W., Hunsicker, P. R., Cacheiro, N. L. A., Kwon, B. S., Jackson, I. J., and Russell, L. B. (1990a). Genetic and molecular analysis of chlorambucil-induced germ-line mutations in the mouse. Proc. Nat. Acad. Sci. USA 87: 1416-1420.

Rinchik, E. M., Carpenter, D. A., and Selby, P. B. (1990b). A strategy for fine-structure functional analysis of a 6- to 11-centimorgan region of mouse chromosome 7 by high-efficiency mutagenesis. Proc. Nat. Acad. Sci. USA 87: 896-900.

Rinchik, E. M., and Russell, L. B. (1990). Germ-line deletion mutations in the mouse: tools for intensive functional and physical mapping of regions of the mammalian genome. In Genetic and Physical Mapping, Genome analysis 1, Davies, K. E. and Tilghman, S. M., eds. (Cold Spring Harbor Laboratory Press, Cold Spring Harbor), pp. 121-158.

Robertson, E. J. (1991). Using embryonic stem cells to introduce mutations into the mouse germ line. Biol Reprod 44: 238-45.

Röhme, D., Fox, H., Herrmann, B., Frischauf, A.-M., Edström, J.-E., Mains, P., Silver, L. M., and Lehrach, H. (1984). Molecular clones of the mouse t complex derived from microdissected metaphase chromosomes. Cell 36: 783-788.

Rossant, J., Vijh, M., Siracusa, L. D., and Chapman, V. M. (1983). Identification of embryonic cell lineages in histological sections of M. musculus<—>M. caroli chimaeras. J. Embryol. Exp. Morph. 73: 179-191.

Rossi, J. M., Burke, D. T., Leung, J. C., Koos, D. S., Chen, H., and Tilghman, S. M. (1992). Genomic analysis using a yeast artificial chromosome library with mouse DNA inserts. Proc Natl Acad Sci U S A 89: 2456-60.

Rowe, F. P. (1981). Wild house mouse biology and control. Symp. zool. Soc. London 47: 575-589.

Rugh, R. (1968). The Mouse: Its Reproduction and Development. (Oxford University Press, New York).

Russell, E. S. (1978). Origins and history of mouse inbred strains: contributions of Clarence Cook Little. In Origins of Inbred Mice, Morse, H. C., eds. (Academic Press, New York), pp. 33-43.

Russell, E. S. (1985). A history of mouse genetics. Ann. Rev. Genet. 19: 1-28.

Russell, L. B. (1990). Patterns of mutational sensitivity to chemicals in poststem-cell stages of mouse spermatogenesis. Prog Clin Biol Res 340: 101.

Russell, L. B., Hunsicker, P. R., Cacheiro, N. L. A., Bangham, J. W., Russell, W. L., and Shelby, M. D. (1989). Chlorambucil effectively induces deletion mutations in mouse germ cells. Proc. Natl. Acad. Sci. U.S.A. 86: 3704-3708.

Russell, L. B., Russell, W. L., Rinchik, E. M., and Hunsicker, P. R. (1990). Factors affecting the nature of induced mutations. In Biology of Mammalian Germ Cell Mutagenesis, Allen, J. W., Bridges, B. A., Lyon, M. F., Moses, M. J., and Russell, L. B., eds. (Cold Spring Harbor Press, Cold Spring Harbor), pp. 271-289.

Russell, W. L., Hunsicker, P. R., Raymer, G. D., Steele, M. H., Stelzner, K. F., and Thompson, H. M. (1982). Dose response curve for ethylnitrosourea specific-locus mutations in mouse spermatogonia. Proc. Nat. Acad. Sci. USA 79: 3589-3591.

Russell, W. L., and Hurst, J. G. (1945). Pure strain mice born to hybrid mothers following ovarian transplantation. Proc. Nat. Acad. Sci. USA 31: 267-273.

Russell, W. L., Kelly, P. R., Hunsicker, P. R., Bangham, J. W., Maddux, S. C., and Phipps, E. L. (1979). Specific-locus test shows ethylnitrosourea to be the most potent mutagen in the mouse. Proc. Nat. Acad. Sci. USA 76: 5918-5922.

Ruvinsky, A., Agulnik, A., Agulnik, S., and Rogachova, M. (1991). Functional analysis of mutations of murine chromosome 17 with the use of tertiary trisomy. Genetics 127: 781-788.

Sage, R. D. (1981). Wild mice. In The Mouse in Biomedical Research, Vol. 1, Foster, H. L., Small, J. D., and Fox, J. G., eds. (Academic Press, N.Y.), pp. 40-90.

Sage, R. D. (1986). Wormy mice in a hybrid zone. Nature 324: 60-63.

Sage, R. D., Whitney, J. B., and Wilson, A. C. (1986). Genetic analysis of a hybrid zone between domesticus and musculus mice (Mus musculus complex): Hemoglobin polymorphisms. Curr. Topics Micro. Immunol. 127: 75-85.

Saiki, R. K., Bugawan, T. L., Horn, G. T., Mullis, K. B., and Erlich, H. A. (1986). Analysis of enzymatically amplified beta-globin and HLA-DQ alpha DNA with allele-specific oligonucleotide probes. Nature 324: 163-166.

Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual. 2nd (Cold Spring Harbor Laboratory, Cold Spring Harbor).

Sapienza, C. (1989). Genome imprinting and dominance modification. Ann NY Acad Sci 534: 24-38.

Sapienza, C. (1991). Genome imprinting and carcinogenesis. Biochem. Biophys. Acta 1072: 51-61.

Scalenghe, F., Turco, E., Edstrom, J. E., Pirotta, V., and Melli, M. (1981). Microdissection and cloning of DNA from a specific region of Drosophila melanogaster polytene chromosomes. Chromosoma 82: 205-216.

Schedl, A., Montoliu, L., Kelsey, G., and Schütz, G. (1993). A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice. Nature 362: 258-261.

Schwartz, D. C., and Cantor, C. R. (1984). Separation of yeast chromosome-sized DNAs by pulsed field gel electrophoresis. Cell 37: 67-75.

Schwarz, D. C., and Cantor, C. R. (1984). Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis. Cell 37: 67-75.

Searle, A. G. (1982). The genetics of sterility in the mouse. In Genetic Control of Gamete Production and Function, Crosignani, P. G. and Rubin, B. L., eds. (Academic Press, London), pp. 93-114.

Searle, A. G. (1989). Chromosomal variants: numerical variants and structural rearrangements. In Genetic Variants and Strains of the Laboratory Mouse., Lyon, M. F. and Searle, A. G., eds. (Oxford University Press, Oxford), pp. 582-616.

Sedivy, J. M., and Joyner, A. L. (1992). Gene Targeting. (W.H. Freeman, New York).

Seldin, M. F., Howard, T. A., and D’Eustachio, P. (1989). Comparison of linkage maps of mouse chromosome 12 derived from laboratory strain intraspecific and Mus spretus interspecific backcrosses. Genomics 5: 24-28.

Serikawa, T., Montagutellie, X., Simon-Chazottes, D., and Guénet, J.-L. (1992). Polymorphisms revealed by PCR with single, short-sized, arbitrary primers are reliable markers for mouse and rat gene mapping. Mammal. Genome 3: 65-72.

Shedlovsky, A., King, T. R., and Dove, W. F. (1988). Saturation germ line mutagenesis of the murine t region including a lethal allele at the quaking locus. Proc Natl Acad Sci U S A 85: 180-4.

Sheehan, P. M., Fastovsky, D. E., Hoffmann, R. G., Berghaus, C. B., and Gabriel, D. L. (1991). Sudden extinction of the dinosaurs: Latest Cretaceous, Upper Great Plains, U.S.A. Science 254: 835-839.

Sheffield, V. C., Beck, J. S., Kwitek, A. E., Sandstrom, D. W., and Stone, E. M. (1993). The sensitivity of single-strand conformation polymorphism analysis for the detection of single base substitutions. Genomics 16: 325-332.

Sheffield, V. C., Cox, D. R., Lerman, L. S., and Myers, R. M. (1989). Attachment of a 40-base pair G + C-rich sequence (GC-clamp) to genomic DNA fragments by the polymerase chain reaction results in improved detection of single-base changes. Proc. Nat. Acad. Sci. USA 86: 232-236.

Sheppard, R., Montagutelli, X., Jean, W., Tsai, J.-Y., Guenet, J.-L., Cole, M. D., and Silver, L. M. (1991). Two-dimensional gel analysis of complex DNA families: Methodology and apparatus. Mammal. Genome 1: 104-111.

Sheppard, R. D., and Silver, L. M. (1993). Methods for two-dimensional analysis of repetitive DNA families. In Guides to Techniques in Mouse Development, Methods in Enzymology 225, Wassarman, P. M. and DePamphilis, M. L., eds. (Academic Press, San Diego), pp. 701-715.

Shizuya, H., Birren, B., Kim, U.-J., Mancino, V., Slepak, T., Tachiiru, Y., and Simon, M. (1992). Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector. Proc. Nat. Acad. USA 89: 8794-8797.

Silver, J. (1985). Confidence limits for estimates of gene linkage based on analysis using recombinant inbred strains and backcrosses. J. Hered. 76: 436-440.

Silver, J., and Buckler, C. E. (1986). Statistical considerations for linkage analysis using recombinant inbred strains and backcrosses. Proc. Nat. Acad. Sci. USA 83: 1423-1427.

Silver, L. M. (1985). Mouse t haplotypes. Ann. Rev. Genet. 19: 179-208.

Silver, L. M. (1986). A software package for record-keeping and analysis of a breeding mouse colony. J. Hered. 77: 479.

Silver, L. M. (1990). At the crossroads of developmental genetics: the cloning of the classical mouse t locus. Bioessays 12: 377-380.

Silver, L. M. (1993a). The peculiar journey of a selfish chromosome: mouse t haplotypes and meiotic drive. Trends in Genetics 9: 250-254.

Silver, L. M. (1993b). Recordkeeping and database analysis of breeding colonies. In Guides to Techniques in Mouse Development, Methods in Enzymology Vol. 225, Wassarman, P. M. and DePamphilis, M. L., eds. (Academic Press, San Diego), pp. 3-15.

Silver, L. M., Hammer, M., Fox, H., Garrels, J., Búcan, M., Herrmann, B., Frischauf, A. M., Lehrach, H., Winking, H., Figueroa, F., and Klein, J. (1987). Molecular evidence for the rapid propagation of mouse t haplotypes from a single, recent, ancestral chromosome. Mol. Biol. Evol. 4: 473-482.

Silver, L. M., Nadeau, J. H., and Goodfellow, P. N. (1993). Encyclopedia of the Mouse Genome III. Mammal. Genome 4 (special issue): S1-S283.

Silver, L. M., Uman, J., Danska, J., and Garrels, J. I. (1983). A diversified set of testicular cell proteins specified by genes within the mouse t complex. Cell 35: 35-45.

Silvers, W. K. (1979). The Coat Colors of the Mouse. (Springer-Verlag, New York).

Simmler, M.-C., Cox, R. D., and Avner, P. (1991). Adaptation of the interspersed repetitive sequence polymerase chain reaction to the isolation of mouse DNA probes from somatic cell hybrids on a hamster background. Genomics 10: 770-778.

Singer, M. F. (1982). SINEs and LINEs: highly repeated short and long interspersed sequences in mammalian genomes. Cell 28.

Siracusa, L. D., Jenkins, N. A., and Copeland, N. G. (1991). Identification and applications of repetitive probes for gene mapping in the mouse. Genetics 127: 169-179.

Slizynski, B. M. (1954). Chiasmata in the male mouse. J. Genet. 53: 597-605.

Smithies, O. (1993). Animal models of human genetic diseases. Trends Genet. 9: 112-116.

Snell, G. D., eds. (1941). Biology of the Laboratory Mouse 1rst edition (Blakiston Co., New York).

Snell, G. D. (1978). Congenic resistant strains of mice. In Origins of Inbred Mice, Morse, H. C., eds. (Academic Press, New York), pp. 1-31.

Snell, G. D., and Reed, S. (1993). William Ernest Castle, pioneer mammalian geneticist. Genetics 133: 751-753.

Snouwaert, J. N., Brigman, K. K., Latour, A. M., Malouf, N. N., Boucher, R. C., Smithies, O., and Koller, B. H. (1992). An animal model for cystic fibrosis made by gene targeting. Science 257: 1083-1088.

Sokal, R. R., Oden, N. L., and Wilson, C. (1991). Genetic evidence for the spread of agriculture in Europe by demic diffusion. Nature 351: 143-145.

Soller, M. (1991). Mapping quantitative trait loci affecting traits of economic importance in animal populations using molecular markers. In Gene-mapping techniques and applications, Schook, L. B., Lewin, H. A., and McLaren, D. G., eds. (Marcel Dekker Inc., New York), pp. 21-49.

Stallings, R. L., Ford, A. F., Nelson, D., Torney, D. C., Hildebrand, C. E., and Moyzis, R. K. (1991). Evolution and distribution of (GT)n repetitive sequences in mammalian genomes. Genomics 10: 807-815.

Steinmetz, M., Uematsu, Y., and Fischer-Lindhal, K. (1987). Hotspots of homologous recombination in mammalian genomes. Trends Genet. 3: 7-10.

Stevens, L. C. (1957). A modification of Robertson’s technique of homoiotopic ovarian transplantation in mice. Transplant. Bull. 4: 106-107.

Strong, L. C. (1978). Inbred mice in science. In Origins of Inbred Mice, Morse, H. C., eds. (Academic Press, New York),

Sturtevant, A. H. (1913). The linear arrangement of six sex-linked factors in Drosophila, as shown by their mode of association. J. Exper. Zool. 14: 43-59.

Taketo, M., Schroeder, A. C., Mobraaten, L. E., Gunning, K. B., Hanten, G., Fox, R. R., Roderick, T. H., Stewart, C. L., Lilly, F., Hansen, C. T., and Overbeek, P. A. (1991). FVB/N: An inbred mouse strain preferable for transgenic analyses. Proc. Nat. Acad. Sci. USA 88: 2065-2069.

Talbot, D., Collis, P., Antoniou, M., Vidal, M., Grosveld, F., and Greaves, D. R. (1989). A dominant control region from the human b-globin locus conferring integration site-independent gene expression. Nature 338: 352-355.

Taylor, B. A. (1978). Recombinant inbred strains: use in gene mapping. In Origins of Inbred Mice, Morse, H. C., eds. (Academic Press, New York), pp. 423-438.

Townes, T. M., and Behringer, R. R. (1990). Human globin locus activation region (LAR): role in temporal control. Trends Genet. 6: 219-223.

Trask, F. (1991). Fluorescence in situ hybridization. Trend. Genet. 7: 149-155.

Tucker, P. K., Lee, B. K., Lundrigan, B. L., and Eicher, E. M. (1992). Geographic origin of the Y chromosome in "old" inbred strains of mice. Mammal. Genome 3: 254-261.

Updike, J. (1991). Introduction. In The Art of Mickey Mouse, Yoe, C. and Morra-Yoe, J., eds. (Hyperion, New York),

Valancius, V., and Smithies, O. (1991). Testing an "in-out" targeting procedure for making subtle genomic modifications in mouse embryonic stem cells. Mol. Cell. Bio. 11: 1402-1408.

van Deursen, J., and Wieringa, B. (1992). Targeting of the creatine kinase M gene in embryonic stem cells using isogenic and nonisogenic vectors. Nuc. Acids Res. 20: 3815-3820.

Vanlerberghe, F., Boursot, P., Catalan, J., Gerasimov, S., Bonhomme, F., Botev, B. A., and Thaler, L. (1988). Analyse génétique de la zone d’hybridation entre les deux sous-espèces de souris Mus musculus domesticus et Mus musculus musculus en Bulgarie. Genome 30: 427-437.

Wagner, E. F., Stewart, T. A., and Mintz, B. (1981a). The human beta-globin gene and a functional thymidine kinase gene in developing mice. Proc. Nat. Acad. Sci. 78: 5016-5020.

Wagner, T. E., Hoppe, P. C., Jollick, J. D., Scholl, D. R., Hodinka, R. L., and Gault, J. B. (1981b). Microinjection of a rabbit beta-globin gene into zygotes and its subsequent expression in adult mice and their offspring. Proc. Nat. Acad. Sci. 78: 6376-6380.

Wallace, M. E. (1981). Wild mice heterozygous for a single Robertsonian translocation. Mouse News Lett. 64: 49.

Wassarman, P. (1993). Mammalian eggs, sperm and fertilisation: dissimilar cells with a common goal. Develop Biol 4: 189-197.

Wassarman, P. M. (1990). Profile of a mammalian sperm receptor. Development 108: 1-17.

Wassarman, P. M., and DePamphilis, M. L., eds. (1993). Guide to Techniques in Mouse Development (Academic Press, San Diego).

Watson, J. D., and Tooze, J. (1981). The DNA Story: a Documentary History of Gene Cloning. (W. H. Freeman, San Francisco).

Watson, M. L., D’Eustachio, P., Mock, B. A., Steinberg, A. D., Morse, H. C., Oakey, R. J., Howard, T. A., Rochelle, J. M., and Seldin, M. F. (1992). A linkage map of mouse chromosome 1 using an interspecific cross segregating for the gld autoimmunity mutation. Mammal. Genome 2: 158-171.

Weber, J. L. (1990). Informativeness of human (dC-dA)n•(dG-dT)n polymorphisms. Genomics 7: 524-530.

Weber, J. L., and May, P. E. (1989). Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction. Am. J. Hum. Genet. 44: 388-396.

Weber, J. L., Wang, Z., Hansen, K., Stephenson, M., Kappel, C., Salzman, S., Wilkie, P. J., Keats, B., Dracopoli, N. C., Brandriff, B. F., and Olsen, A. S. (1993). Evidence for human meiotic recombination interference obtained through construction of a short tandem repeat-polymorphism linkage map of chromosome 19. Am. J. Hum. Genet. 53: 1079-1095.

Weinberg, R. A. (1991). Tumor suppressor genes. Science 254: 1138-1146.

Weiss, R. (1991). Hot prospect for new gene amplifier: How LCR works. Science 254: 1292-1293.

Welsh, J., and McClelland, M. (1990). Fingerprinting genomes using PCR with arbitrary primers. Nucl. Acids Res. 18: 7213-7218.

Welsh, J., Peterson, C., and McClelland, M. (1991). Polymorphisms generated by arbitrarily primed PCR in the mouse: applications to strain identification and genetic mapping. Nucl. Acids Res. 19: 303-306.

West, J. D., Frels, W. I., Papaioannou, V. E., Karr, J. P., and Chapman, V. M. (1977). Development of interspecific hybrids of Mus. J. Embryol. exp. Morph. 41: 233-243.

Whittingham, D. G., and Wood, M. J. (1983). Reproductive Physiology. In The Mouse in Biomedical Research, Vol. 3, Foster, H. L., Small, J. D., and Fox, J. G., eds. (Academic Press, NY), pp. 137-164.

Williams, J. G. K., Kubelik, A. R., Livak, K. J., Rafalski, J. A., and Tingey, S. V. (1990). DNA polymorphisms amplified by arbitrary primers are useful as genetic markes. Nucl. Acids Res. 18: 6531-6535.

Wills, C. (1992). Exons, Introns, and Talking Genes: The Science Behind the Human Genome Project. (Basic Books, New York).

Wilson, A. C., Ochman, H., and Prager, E. M. (1987). Molecular scale for evolution. Trends Genet. 3: 241-247.

Wimer, R. E., and Fuller, J. L. (1966). Patterns of behavior. In Biology of the Laboratory Mouse, Green, E. L., eds. (McGraw-Hill, New York), pp. 629-653.

Winking, H., and Silver, L. M. (1984). Characterization of a recombinant mouse t haplotype that expresses a dominant maternal effect. Genetics 108: 1013-1020.

Womack, J. E. (1979). Single gene differences controlling enzyme properties in the mouse. Genetics 92: s5-s12.

Wood, S. A., Pascoe, W. S., Schmidt, C., Kemler, R., Evans, M. J., and Allen, N. D. (1993). Simple and efficient production of embryonic stem cell—embryo chimeras by coculture. Proc Natl Acad Sci USA 90: 4582-4585.

Woodward, S. R., Sudweeks, J., and Teuscher, C. (1992). Random sequence oligonucleotide primers detect polymorphic DNA products which segregate in inbred strains of mice. Mammal. Genome 3: 73-78.

Woychik, R. P., Wassom, J. S., and Kingsbury, D. (1993). TBASE: a computerized database for transgenic animals and targeted mutations. Nature 363: 375-376.

Wright, S. (1952). The genetics of quantitative variability. In Quantitative Genetics, Reeve, E. C. R. and Waddington, C. H., eds. (H.M. Stat. Office, London), pp. 5-41.

Wright, S. (1966). Mendel’s ratios. In The Origin of Genetics: A Mendel Source Book, Stern, C. and Sherwood, E. R., eds. (W.H. Freeman, San Francisco),

Yamazaki, K., Beauchamp, G. K., Matsuzaki, O., Kupniewski, D., Bard, J., Thomas, L., and Boyse, E. A. (1986). Influence of a genetic difference confined to mutation of H-2K on the incidence of pregnancy block in mice. Proc. Nat. Acad. Sci. 83: 740-741.

Yonekawa, H., Moriwaki, K., Gotoh, O., Hayashi, J.-I., Watanabe, J., Miyashita, N., Petras, M. L., and Tagashira, Y. (1981). Evolutionary relationships among five subspecies of Mus musculus based on restriction enzyme cleavage patterns of mitochondrial DNA. Genetics 98: 801-816.

Yonekawa, H., Moriwaki, K., Gotoh, O., Miyashita, N., Matsushima, Y., Shi, L., Cho, W. S., Zhen, X.-L., and Tagashira, Y. (1988). Hybrid origin of Japanese mice "Mus musculus molossinus": evidence from restriction analysis of mitochondrial DNA. Mol. Biol. Evol. 5: 63-78.

Yonekawa, H., Moriwaki, K., Gotoh, O., Watanabe, J., Hayashi, J.-I., Miyashita, N., Petras, M. L., and Tagashira, Y. (1980). Relationship between laboratory mice and subspecies mus musculus domesticus based on restriction endonuclease cleavage patterns of mitochondrial DNA. Japan. J. Genetics 55: 289-296.

Zhang, L., Cui, X., Schmitt, K., Hubert, R., Navidi, W., and Arnheim, N. (1992). Whole genome amplification from a single cell: implications for genetic analysis. Proc Natl Acad Sci USA 89: 5847-5851.

Zhang, Y., and Tycko, B. (1992). Monoallelic expression of the human H19 gene. Nature Genetics 1: 40-44.

Zimmerer, E. J., and Passmore, H. C. (1991). Structural and genetic properties of the Eb recombinational hotspot in the mouse. Immunogenetics 33: 132-40.

Zoghbi, H. Y., and Chinault, A. C. (1994). Generation of YAC contigs by walking. In YAC Libraries, A User’s Guide, Nelson, D. L. and Brownstein, B. H., eds. (W.H. Freeman and Company, New York),

Zurcher, C., van Zwieten, M. J., Solleveld, H. A., and Hollander, C. F. (1982). Aging Research. In The Mouse in Biomedical Research, Vol. 4, Foster, H. L., Small, J. D., and Fox, J. G., eds. (Academic Press, NY), pp. 11-35.