A course on reflections from crystal planes.
A review of Fourier Transforms.
An excellent tutorial on structure factors can be found in the UK.
A tutorial illustrating diffraction, including reciprocal lattices and the Ewald called XRay-view.
Yet another tutorial on X-Ray & Neutron Diffraction.
Study Guides:
These on-line additions to your study guides will rely on the use of several types of tools. This first is a browser based tool for a quick first-look at the structures called Chime. The next type of tool is a molecular structure program. The software that will be most heavily relied upon is a program called Swiss-PDB. This is a free program that (in my opinion) out-competes the most expensive packages. If you would like to try other packages, I can recommend Grasp, Rasmol, Insight, or Mol Mol. Some will run on other platforms (such as Unix) if you do not have access to a Mac or a PC on which to run Swiss-PDB.
Study
Guide1:
Doyle et al.,Science, 3 April 1998
Color Images: |
For a Chime overview : Click here.
Download Swiss-PDB'd protein : Click here. Download the raw coordinates : Click here. NOTE: To download coordinates (not the Chime overview) you need to click and hold the button down until you get a menu. At the menu select Save this link as... |
Color Images: |
For a Chime overview : Click here.
Download Swiss-PDB'd protein : Click here. Download the raw coordinates : Click here. NOTE: To download coordinates (not the Chime overview) you need to click and hold the button down until you get a menu. At the menu select Save this link as... |
MacKinnon et al., Science, 18 December 1998
Color Images: |
For a Chime overview : Click here.
Download Swiss-PDB'd protein : Click here. Download the raw coordinates : Click here. NOTE: To download coordinates (not the Chime overview) you need to click and hold the button down until you get a menu. At the menu select Save this link as... |
Lecture Transparencies:
Gating Reference: Liemann et al., J. Molecular Biology, 1996, vol. 258, p.555-561. |
For a Chime overview : Click here.
Download Swiss-PDB'd protein : Click here. Download the raw coordinates : Click here. NOTE: To download coordinates (not the Chime overview) you need to click and hold the button down until you get a menu. At the menu select Save this link as... |
Lecture Transparencies:
|
For a Chime overview : Click here.
Download Swiss-PDB'd protein : Click here. Download the raw coordinates : Click here. NOTE: To download coordinates (not the Chime overview) you need to click and hold the button down until you get a menu. At the menu select Save this link as... |
Wang et al., Nat.Struct.Bio., June 1998
Color Images:
Lecture Transparencies: |
For a Chime overview : Click here.
Download Swiss-PDB'd protein : Click here. Download the raw coordinates : Click here. NOTE: To download coordinates (not the Chime overview) you need to click and hold the button down until you get a menu. At the menu select Save this link as... |
Lecture Transparencies: |
For a Chime overview : Click here.
Download Swiss-PDB'd protein : Click here. Download the raw coordinates : Click here. NOTE: To download coordinates (not the Chime overview) you need to click and hold the button down until you get a menu. At the menu select Save this link as... |
Lecture Transparencies: |
For a Chime overview : Click here.
Download Swiss-PDB'd protein : Click here. Download the raw coordinates : Click here. NOTE: To download coordinates (not the Chime overview) you need to click and hold the button down until you get a menu. At the menu select Save this link as... |
Lecture Transparencies: |
For a Chime overview : Click here.
Download Swiss-PDB'd protein : Click here. Download the raw coordinates : Click here. NOTE: To download coordinates (not the Chime overview) you need to click and hold the button down until you get a menu. At the menu select Save this link as... |
Armstrong et al., Nature, 29 October1998-Glutamate Receptor
Color Images:
Lecture Transparencies: |
For a Chime overview : Click here.
Download Swiss-PDB'd protein : Click here. Download the raw coordinates : Click here. NOTE: To download coordinates (not the Chime overview) you need to click and hold the button down until you get a menu. At the menu select Save this link as... |
Lecture Transparencies: |
For a Chime overview : Click here.
Download Swiss-PDB'd protein : Click here. Download the raw coordinates : Click here. NOTE: To download coordinates (not the Chime overview) you need to click and hold the button down until you get a menu. At the menu select Save this link as... |
Lecture Transparencies: |
For a Chime overview : Click here.
Download Swiss-PDB'd protein : Click here. Download the raw coordinates : Click here. NOTE: To download coordinates (not the Chime overview) you need to click and hold the button down until you get a menu. At the menu select Save this link as... |
Lecture Transparencies: NOTE: this is not the final docking |
For a Chime overview : Click here.
Download Swiss-PDB'd protein : Click here. Download the raw coordinates : Click here. NOTE: To download coordinates (not the Chime overview) you need to click and hold the button down until you get a menu. At the menu select Save this link as... |
Lecture Transparencies: |
For a Chime overview : Click here.
Download Swiss-PDB'd protein : Click here. Download the raw coordinates : Click here. NOTE: To download coordinates (not the Chime overview) you need to click and hold the button down until you get a menu. At the menu select Save this link as... |
Nogales et al., Nature, 8 January 1998
Color Images:
Lecture Transparencies: |
For the Dimer Building:
Download Swiss-PDB'd structure of a-tubulin: Click here. Download Swiss-PDB'd structure of b-tubulin: Click here. The Usual Stuff:
Download Swiss-PDB'd protein : Click here. Download the raw coordinates : Click here. NOTE: To download coordinates (not the Chime overview) you need to click and hold the button down until you get a menu. At the menu select Save this link as... |
Kull et al., Nature, 11 April 1996
Color Images:
Lecture Transparencies: |
For a Chime overview : Click here.
Download Swiss-PDB'd protein : Click here. Download the raw coordinates : Click here. NOTE: To download coordinates (not the Chime overview) you need to click and hold the button down until you get a menu. At the menu select Save this link as... |
Sablin et al., Nature, 11 April 1996
Color Images:
Lecture Transparencies: |
For the Modeling:
Download Swiss-PDB'd structure of Ncd monomer: Click here. The Usual Stuff:
Download Swiss-PDB'd protein : Click here. Download the raw coordinates : Click here. NOTE: To download coordinates (not the Chime overview) you need to click and hold the button down until you get a menu. At the menu select Save this link as... |
Sosa et al., Cell, 25 July 1997
Color Images:
Rayment et al., Science, 1993
Lecture Transparencies: